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              Congenital Heart Malformations













                Key Points

                •	Congenital	heart	malformations	occur	in	a	small	proportion	of	feline	cardiology	patients	(<10%	of	cases).
                •	In	general,	echocardiography	will	be	needed	to	diagnose	the	exact	malformation	because	there	is	a	tremendous	amount	of
                  overlap	between	physical	examination,	electrocardiographic,	and	radiographic	findings	for	most	malformations.
                •	Treatment	is	generally	directed	at	controlling	clinical	signs	that	may	develop	due	to	heart	failure	or	arrhythmias	because
                  treatment	of	the	primary	defect	is	not	usually	possible.








              INTRODUCTION                                       malformations are patent ductus arteriosus, aortic ste-
                                                                 nosis, tetralogy of Fallot, atrial septal defect, common
              Congenital  heart  malformations  are  developmental   atrioventricular  canal,  and  pulmonic  stenosis  (Riesen
              defects of the heart that are present at birth. They may   et al. 2007).
              be inherited or may develop spontaneously without any
              known familial pattern.
                 In general, feline congenital heart disease is much less   HISTORY AND CHIEF COMPLAINT
              common than acquired heart diseases like the cardiomy-  Many kittens and cats with congenital heart malforma-
              opathies.  Approximately  5%  of  cats  examined  by  the   tions are asymptomatic, but in others, clinical signs may
              cardiology service at the School of Veterinary Medicine   be intermittent and include exercise intolerance, syncope,
              at  the  University  of  California-Davis  over  a  10-year   and dyspnea. Animals that have progressed to the point
              period were diagnosed with a congenital heart malfor-  of  development  of  congestive  heart  failure  may  show
              mation  (MacDonald  2006).  A  recent  study  from  two   other  vague  clinical  signs  including  loss  of  appetite,
              veterinary cardiology services in Switzerland identified   depression, and exercise intolerance.
              that 12% of the feline cardiology cases had congenital
              heart disease (Riesen et al. 2007). A prospective study of   PHYSICAL EXAMINATION
              circulating  biomarkers  in  cats  presented  to  a  private
              referral practice revealed a ratio of myocardial disease to   In many cases, careful evaluation of a juvenile cat with
              congenital heart malformations of 23:1 (Ettinger 2010).  a  congenital  heart  malformation  defect  will  identify  a
                 The most commonly reported feline congenital heart   heart murmur and/or arrhythmia, although some cases
              malformations are mitral and tricuspid valve malforma-  may not have any auscultatory abnormalities. The loca-
              tions  and  ventricular  septal  defects,  although  which   tion and timing of the murmur can help to narrow the
              defect is actually more common seems to vary depend-  differential diagnosis list substantially (see Chapter 1).
              ing on the study. Less commonly reported feline heart   Cyanosis may be noted in some cases.



              Feline Cardiology, First Edition. Etienne Côté, Kristin A. MacDonald, Kathryn M. Meurs, Meg M. Sleeper.
              © 2011 John Wiley & Sons, Inc. Published 2011 by John Wiley & Sons, Inc.

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