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Nervous System Toxicity Chapter | 12  211




  VetBooks.ir  TABLE 12.3 (Continued)                            TABLE 12.3 (Continued)

               Loperamide
                                                                 Essential oils
               Meperidine                                        Hydrocarbons
               Morphine                                          Indoxacarb
               Naloxone                                          Macadamia nuts
               Oxymorphone                                       Nitrofuran
               Oxycodone                                         Tick paralysis
               Tramadol
               Multiple/Miscellaneous MOAs
               Ageratina (white snakeroot): tremetone
                                                                comprehensive, yet certainly not exhaustive, list of neuro-
               Astragalus/Oxytropis (locoweed): miserotoxin
                                                                toxicants grouped by mechanism or site of action where
               Bovine bonkers/ammoniated feed): 4-methylimidazole  known.
               Brunfelsia (yesterday, today and tomorrow plant):  The extent to which a neurotoxicant exerts its effects
               brunfelsamidine                                  depends on a variety of factors including dose, species,
                                                                age, genetics, underlying diseases, drug therapy, diet,
               Cycas (sago palm): β-methylamino-L-alanine
                                                                stress, and concurrent toxicoses. Veterinary practitioners
               5-Fluorouracil/1080
                                                                should be aware of these underlying susceptibilities and
               Lead                                             the most common mechanisms by which neurotoxicants
                                                                act so that toxicoses may be avoided or appropriately
               Macrozamia (cycad palms): β-oxalylamino-L-alanine
                                                                diagnosed and successfully treated when they do occur.
               Mercury
               Methylxanthines, Guarana (adenosine receptor antagonists)
                                                                REFERENCES
               Phenothiazines (anticholinergic, antihistaminic, α-adrenergic
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                                                                  Casarett & Doull’s Toxicology: The Basic Science of Poisons, sixth
               Stipa (sleepy grass): ergot alkaloids
                                                                  ed. McGraw-Hill, New York, pp. 535 563.
               Metabolic                                        Arnot, L.F., Veale, D.J., Steyl, J.C., Myburgh, J.G., 2011. Treatment
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                                                                  Afr. Vet. Assoc. 82 (4), 232 238.
               Cyanide                                          Bailey, E.M., 2006. Botulinum. In: Peterson, M.E., Talcott, P.A. (Eds.),
                                                                  Small Animal Toxicology, second ed. Elsevier, Inc, St. Louis,
               Zinc phosphide
                                                                  pp. 603 608.
               Thiamine Deficiency/Thiaminase Excess
                                                                Beasley, V.R., 1999. Veterinary Toxicology. International Veterinary
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                                                                Blodgett, D.J., 2006. Organophosphorus and carbamate insecticides.
               Pteridium (bracken fern)
                                                                  In: Peterson, M.E., Talcott, P.A. (Eds.), Small Animal Toxicology,
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                                                                Bossart, G.D., Baden, D.G., Ewing, R.Y., et al., 1998. Brevetoxicosis in
               Excess dietary sulfur
                                                                  manatees (Trichechus manatus latirostris) from the 1996 epizootic:
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               Bromethalin                                        Pathol. 26 (2), 276 282.
                                                                Burrows, G.E., Tyrl, R.J., 2013. Toxic Plants of North America. second
               Hexachlorophene
                                                                  ed. John Wiley & Sons, Inc, Ames.
               Trialkyltin                                      Capen, C.C., 2001. Toxic responses of the endocrine system. In: Klaassen,
                                                                  C.D. (Ed.), Casarett & Doull’s Toxicology: The Basic Science of
               Unknown Etiology/MOA
                                                                  Poisons, sixth ed. McGraw-Hill, New York, pp. 711 759.
               Desert spike                                     Coleman, E.S., 1998. Clostridial neurotoxins: tetanus and botulism.
               Diethyltoluamide (DEET)                            Compend. Contin. Educ. Pract. Vet. 20 (10), 1089 1097.
                                                                Craig, M.S., Gupta, R.C., Candery, T.D., Britton, D.A., 2005. Human
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