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Concepts in Veterinary Toxicology Chapter | 1  5




  VetBooks.ir  half of the book indicating the importance of poisonous  ogy as part of the National Veterinary Medical Series for
                                                                  Osweiler (1996) has authored a text focused on toxicol-
             plants in that era of veterinary medicine.
                Many early students in veterinary medicine in the
                                                                Independent Study. It has been widely used by individuals
             United States used textbooks prepared for physicians such  preparing for the National Board Examinations for
             as Kobert (1897), Practical Toxicology for Physicians  Veterinary Medical Licensing. Roder (2001) has prepared a
             and Students. It was also common to use either textbooks  text, Veterinary Toxicology,aspartofaseries, The Practical
             in pharmacology or veterinary pharmacology that con-  Veterinarian. This was followed by a version edited by
             tained a brief coverage of toxicology. Indeed, few veteri-  Chapman and Campbell, 2011. More recently, two updates
             nary medical colleges prior to the 1950s had full-time  have been released: Blackwell’s Five-Minute Veterinary
             veterinary toxicologists on their faculty. Lectures on toxi-  Consult Clinics Companion: Small Animal Toxicology
             cology were usually included in courses in pharmacology,  (Hovda et al., 2016) and Canine and Feline (Tilley and
             pathology, and clinical medicine.                  Smith, 2015). Plumlee (2004) has edited Clinical Veterinary
                The first veterinary toxicology text I personally used  Toxicology, and Peterson and Talcott have edited three edi-
             wasauthoredbyR.John Garner (1957) who was then a   tions of Small Animal Toxicology, the most recent edited of
             Senior Lecturer in Chemical Pathology (Veterinary) at the  whichwas publishedin2012(Peterson and Talcott, 2012).
             University of Bristol in the United Kingdom and later Head  Small Animal Toxicology Essentials, first edition, by
             of the Radiobiology Department at the Agricultural  Poppenga and Gwaltney-Brant (2011) is also a valuable
             Research Council Field Station, Compton, Berks, United  reference. In my opinion, the present multiauthored text edi-
             Kingdom. At the Compton Station he conducted pioneering  ted by Ramesh Gupta is the most comprehensive text on
             research on the fate of important radionuclides in domestic  veterinary toxicology published to date. It is encouraging that
             animals. The text by Garner (1957) was intended as a suc-  it is now appearing in a third edition.
             cessor to the third edition of Lander’s Veterinary   There are a number of comprehensive general toxicol-
             Toxicology (Nicholson, 1945). A second edition was pre-  ogy texts available today. I will note five that the serious
             pared by Garner (1961) after he became head of the Public  student of toxicology will find useful to have in their
             Health Section, Radiological Protection Division, UK  reference library. Casarett and Doull’s Toxicology: The
             Atomic  Energy  Authority,  Harwell,  Berks,  United  Basic Science of Poisons edited most recently by
             Kingdom. I visited Garner in 1962 and discussed with him  Klaassen (2013) was first published in 1975 and is now in
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             the release of I  in the 1957 Windscale reactor accident.  its eighth edition. As an aside, I had the opportunity to
             This accident emphasized the importance of the dairy cow  observe first hand Louis Casarett and John Doull planning
             milk pathway for human exposures. Later, Garner came to  the first edition of this new textbook as I served with
             the United States where he was initially associated with  them on the Toxicology Study Section of the National
             Colorado State University directing studies of the long-term  Institute of Health. Unfortunately, Louis Casarett died of
             effects of external radiation on Beagles. I recall asking  cancer before the first edition (Casarett and Doull, 1975)
             Garner in the early 1970s about the possibility of preparing  was completed. I was pleased when John Doull asked me
             a third edition of his veterinary toxicology text. He  to prepare the chapter that Louis had intended to write on
             responded that the field of veterinary toxicology had  radiation toxicology, which I did with my colleague,
             become so broad that it was not readily feasible for a single  Charles Hobbs (Hobbs and McClellan, 1975). Hayes’
             individual to author a text in veterinary toxicology and he  Principles and Methods in Toxicology is now in its sixth
             was not interested in “shepherding a herd of individual  edition (Hayes and Kruger, 2014). Toxicology, edited by
             chapter authors” with specialized knowledge of various  Marquardt et al. (1999) is built on an earlier German text
             aspects of veterinary toxicology. With this textbook, Gupta  by Marquardt and Schafer (1994, 2004). Biological
             has responded to the challenge offered by Garner.  Concepts and Techniques in Toxicology: An Integrated
                Radeleff (1964) authored one of the first veterinary toxi-  Approach edited by Riviere (2006) is a concise textbook.
             cology texts published in the United States. A second edi-  Another pioneer in toxicology, Ernest Hodgeson, has edi-
             tion appeared in 1970. This was followed by a text prepared  ted a textbook that is now in its fourth edition (Hodgeson,
             by Osweiler et al. (1985). Several books published in the  2010). Serious students will also want to be aware of
             1960s became classics on the effects of poisonous plants  a multivolume comprehensive set of toxicology text-
             (Kingsbury, 1954, 1964; Hulbert and Oehme, 1968). Recent  books. The first edition was edited by Sipes and collea-
             books on poisonous plants have been authored by Garland  gues (1997) a 14-volume second edition edited by
             and Barr (1998), Burrows and Tyrl (2006),and Knight and  McQueen (2010). Moreover, there are numerous text and
             Walter (2001). Murphy (1996) has authored a field guide to  reference books available now covering various subspe-
             common animal poisons. It is organized by the organ sys-  cialty areas such as inhalation toxicology, reproductive
             tem affected and then by toxicant.                 and developmental toxicology, and dermal toxicology.
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