Page 1393 - Small Animal Internal Medicine, 6th Edition

CHAPTER 83 Clinical Pathology in Greyhounds and Other Sighthounds 1365

Pathology Laboratory at OSU, and plasma protein concen- aPTT, and FIB concentration), we used two different analyz-
trations were obtained using a refractometer. The results ers, the ACL 200 Coagulation Analyzer (Instrumentation
VetBooks.ir obtained from the three hematology analyzers (CD-3500, Laboratory, Lexington, MA) and Stago Compact Analyzer
(Diagnostica Stago, Parsippany, NJ). RIs are shown in
LaserCyte, and ProCyte) are shown in Table 83.2.
The serum biochemistry profiles were determined using
a COBAS c501 analyzer (Roche Diagnostics, Indianapolis; Table 83.4.
Proposed RIs are summarized in Tables 83.1 through
Table 83.3). For the conventional hemostasis assays (OSPT, 83.4.

TABLE 83.2
Hematology Reference Intervals in Greyhounds*

REFERENCE INTERVAL INSTRUMENTS OTHER REFERENCE INTERVALS †
FOR GREYHOUNDS GREYHOUND: ADVIA DOG:
PARAMETER CD-3500 LASERCYTE PROCYTE 120 AND ADVIA 2120 ADVIA 120

Total leukocytes (×10 /L) 3.3-7.5 4.4-10.8 3.6-6.9 3.38-8.51 5.84-20.26
9
(4.1-15.2) (5.5-16.9) (5.1-16.7)
9
Lymphocytes (×10 /L) 0.4-2.2 0.2-2.5 0.8-2.2 0.57-2.50 2.04-4.66
(1-4.6) (0.5-4.9) (1.1-5.1)
Neutrophils (×10 /L) 2.1-6.1 2.6-7.4 2.1-5.2 2.21-6.48 4.27-9.06
9
(4.1-15.2) (2.0-12.0) (2.9-11.6)
Monocytes (×10 /L) 0.0-0.5 0.3-1.1 0.1-0.3 0.01-0.75 0.24-2.04
9
(0-1.2) (0.3-2.0) (0.2-1.1)
Eosinophils (×10 /L) 0.0-0.6 0.0-1.1 0.0-1.0 0.00-0.31 0.1-1.2
9
(0-1.3) (0.1-1.5) (0.2-1.2)
9
Basophils (×10 /L) 0.0-0.0 (NA) (0.00-0.01) 0.0-0.1 ND ND
(0.0-0.1)
HCT (%) 46.9-62.5 42.7-61.5 51.5-71.0 50.0-68.0 42.0-62.0
(36-54) (37-55) (37.3-61.7)
Hb (g/dL) 16.3-22.0 15.1-20.4 17.4-24.1 16.9-22.8 13.7-20.3
(11.9-18.4) (12.0-18.0) (13.1-20.5)
RBC (×10 /L) 6.7-9.3 6.0-9.4 7.4-10.2 6.67-9.22 5.68-9.08
12
(4.9-8.2) (5.5-8.0) (5.6-8.8)
Reticulocytes (×10 /L) ND 17.2-45.7 10.0-97.7 ND ND
9
(14.7-17.9) (6.6-100.7)
MCV (fL) 66.4-72.0 66.0-78.9 63.0-76.1 69.68-79.67 62.7-74.56
(64-75) (60.0-77.0) (61.6-73.5)
MCHC (g/dL) 34.1-36.0 29.4-38.2 33.1-35.1 ND ND
(32.9-35.2) (30.0-37.5) (32.0-37.9)
MCH (pg) ND 20.9-28.6 21.5-26.2 ND ND
(18.5-30.0) (21.2-25.9)
RDW (%) 14.2-17.2 14.7-15.9 16.0-22.2 ND ND
(13.4-17.0) (14.7-17.9) (13.6-21.7)
Platelet count (×10 /L) 135.4-235.3 117.0-295.0 112.0-204.7 144.5-309.0 173.1-496.5
9
(106-424) (175-500) (148-484)
MPV (fL) ND 6.9-11.8 (NA) 8.6-11.9 ND ND
(8.7-13.2)

NA, Not available; ND, not done; RDW, red blood cell distribution width.
*These were determined at The Ohio State University using three different instruments: CD-3500 Analyzer (Abbott Diagnostics, Santa Clara,
CA) with manual differential cell count; LaserCyte Analyzer (IDEXX Laboratories, Westbrook, ME); and ProCyteDx Analyzer (IDEXX). Instrument
generic reference intervals are shown in parentheses. Additional columns correspond to published reference intervals for Greyhounds
(Campora et al., 2011) and for dogs (Bauer N et al.: Reference intervals and method optimization for variables reflecting hypocoagulatory
and hypercoagulatory states in dogs using the STA Compact automated analyzer, J Vet Diagn Invest 21:803, 2009).
† ADVIA 120 and ADVIA 2120, Siemens Medical Solutions USA, Malvern, Pa.
From Zaldívar-López S et al.: Clinical pathology of Greyhounds and other sighthounds, Vet Clin Pathol 40:414, 2011a.