Page 1070 - Veterinary Immunology, 10th Edition
P. 1070
autocrine growth of the mesangial cells. The TGF-β stimulates
VetBooks.ir production of extracellular matrix. This glomerulonephritis
eventually interferes with glomerular function. By
immunofluorescence, it can be shown that lumpy aggregates of
immune complexes are deposited in capillary walls and on the
epithelial side of the glomerular basement membrane (Fig. 32.10).
FIG. 32.9 The pathogenesis of different forms of immune
complex–mediated glomerulonephritis. Remember, however, that
more than one type of lesion may be present in an animal at the
same time.
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