Page 1234 - Veterinary Immunology, 10th Edition
P. 1234
VetBooks.ir Autoimmune Nephritis
Horses may develop autoantibodies to glomerular basement
membranes resulting in glomerulonephritis and renal failure.
Immunofluorescence studies of affected kidneys show that the
basement membrane is evenly coated with a smooth, linear deposit
of immunoglobulin. The autoantibodies may provoke proliferation
of the glomerular epithelial cells and epithelial crescent formation.
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