Page 25 - Rule Outs in Small Animal Medicine, Problem-oriented Assessment of Problems in Physical Examination and Clinical Pathology, 2nd Edition

Internal Medicine Internal Medicine
General health problems General health problems

VetBooks.ir

Icterus

Prehepatic Hepatic Posthepatic

Increased Disturbance of
degradation of Hepatic dysfunction hepatocellular Bile duct rupture Bile duct obstruction
haemproteins bilirubin transport

– Liver fibrosis Disturbance of – Cholangiohepatitis
Haemoglobin Myoglobin – Liver cirrhosis Lack of glucose the bilirubin – Bile duct
degradation degradation – Liver neoplasia (only horse and cow) transport system carcinoma
– Hepatic lipidosis (by high TNF-α) – Pancreatitis
– Gall bladder
stones

Haemorrhage in Massive destruction of
Haemolysis body cavities or muscle cells (rare in – Severe
haematoma small animals) systemic
inflammation
(e.g. sepsis, FIP)

– Myositis
Extravascular Intravascular – Trauma
haemolysis haemolysis

– Immune-mediated haemolytic – Copper intoxication
anaemia – Tap water enema (cat)
– Babesiosis – Hypophosphataemia (e.g. during therapy
– Haemoplasma infection of diabetic ketoacidosis)
– Severe immune-mediated haemolytic
anaemia
– Severe babesiosis
– Zinc intoxication
– Onion or garlic intoxication
– Destruction (e.g. DIC, caval syndrome,
hemangioendothelioma)

14 15