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166  Bacterial Pyodermas  1465

               subcutaneously  injected  commercial  S.  aureus  phage   atopic dermatitis or cutaneous adverse food reaction,
  VetBooks.ir  lysate antigens (Staphage Lysate®, Delmont Laboratories)   cystic hemorrhagic, bullous lesions are often observed
                                                                  on the chin and interdigital areas. Staphylococci repre-
               may be used as maintenance therapy to reduce or elimi-
               nate recurrence of pyoderma. This treatment is indicated
                                                                  may also be accompanied by infection with Enterococcus,
               in patients with idiopathic or atopic recurrent pyoderma   sent the predominant organism but deep pyoderma
               cases failing to respond to topical maintenance therapy.  Pseudomonas, and Proteus species as well as Escherichia
                                                                  coli. Differentials include dimorphic and opportunistic
                                                                  mycoses, pythiosis, lagenidiosis, neoplasia, foreign
               Deep Pyodermas
                                                                  body,  sterile  pyogranulomatous  dermatitis,  and  other
               Generalized Deep Pyoderma                          bacterial etiologies, including species in the genera
               Generalized deep pyoderma arises due to furunculosis   Mycobacterium, Actinomyces, and Nocardia. Cytologic
               (follicular rupture) and foreign body response directed   presence of numerous extracellular cocci or phagocy-
               at the liberated hair shafts in the dermis. Lesions include   tosed cocci supports the diagnosis. Given the diverse
               nodules, hemorrhagic bullae, ulcers, draining tracts and   clinical differentials and requirement for prolonged
               crusts with variable pain and pruritus (Figures  166.9   treatment, bacterial culture (aerobic and anaerobic)
               and 166.10).                                       and sensitivity, fungal culture, and histopathology are
                 In cats, deep pyoderma most commonly presents in   recommended for definitive diagnosis and appropriate
               the context of chin acne. In short‐coated breeds with   treatment.

                                                                  Canine Acne
                                                                  This disease is typified by deep folliculitis and furuncu-
                                                                  losis affecting the chin and perioral margin, and is a
                                                                  focal form of deep pyoderma. Chin acne usually mani-
                                                                  fests in young dogs between 3 and 12 months of age
                                                                  although it often persists throughout adulthood and
                                                                  may be complicated by concurrent atopic dermatitis or
                                                                  cutaneous adverse food reaction. Breeds with a short,
                                                                  coarse hair coat are predisposed, including boxers,
                                                                  English and French bulldogs, and Boston terriers.
                                                                    Lesions  consist of papules and nodules  that often
                                                                  become erosive and ulcerative with resultant draining
                                                                  tract formation. Hemorrhagic bullae are also common
                                                                  (Figure 166.11).
                                                                    Demodicosis should be ruled out by performing deep
               Figure 166.9  Nonblanching, hemorrhagic, nodular, deep
               staphylococcal pyoderma in a 5‐year‐old Rottweiler with   skin scrapes. Juvenile cellulitis is a differential diagnosis;
               atopic dermatitis.                                 however, classic submandibular lymphadenopathy as well






















               Figure 166.10  Erythematous nodules with ulcers due to deep   Figure 166.11  Nodular, ulcerative, and purulent deep
               Pseudomonas pyoderma on the lateral hindlimb of a 3‐year‐old   staphylococcal pyoderma on the chin of a cane corso dog
               Rottweiler mix.                                    with atopic dermatitis.
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