Page 922 - Clinical Small Animal Internal Medicine

860 Section 9 Infectious Disease

VetBooks.ir + SUPPORTIVE CARE FOR CPV

Control Hydration & Prevent 2° Relieve Pain Maintain Nutrition
Electrolyte Balance Infections • Buprenorphine • Nasoesophageal
• Crystalloids + • Ampicillin feeding**
• Enrofloxacin
• Colloids
• Metronidazole

+ Potassium supplementation is important and should be adjusted based on frequent measurement of serum potassium.
# Ampicillin or cefazolin may be sufficient however improved gram-negative coverage may be needed. There is a risk of cartilage
deformity in puppies treated with fluoroquinolones, however short-term(<7 d)therapy at 5 mg/kg q 24 hours may be warranted
Once the patient is hydrated, aminoglycosides may also be considered for improved gram-negative coverage.
Metronidazole may be used to improve anaerobic coverage if needed.
** Use of the GI tract and trickle feeding is associated with improved survival compared to fasting, and is preferred over
intravenous feeding due to the ability to provide nutrition to enterocytes and due to the risk of sepsis associated with parenteral
nutrition.

Figure 82.1 Supportive care for CPV.

Further Reading

Anderson A, Hartmann K, Leutenegger CM, et al. Role of systematic review of controlled clinical trials. Vet
canine circovirus in dogs with acute haemorrhagic Microbiol 2015; 180: 1–9.
diarrhoea. Vet Rec 2017; 180: 542. Li L, McGraw S, Zhu K, et al. Circovirus in tissues of dogs
Decaro N, Buonavoglia C. Canine parvovirus – a review of with vasculitis and hemorrhage. Emerg Inf Dis 2013; 19:
epidemiological and diagnostic aspects, with emphasis 534–41.
on type 2c. Vet Microbiol 2012; 155: 1–12. Sykes JE. Canine parvovirus infections and other viral
Di Martino B, di Felice E, Ceci C, di Profio F, Marsilio F. enteritides. In: Sykes JE, ed. Canine and Feline Infectious
Canine kobuviruses in diarrhoeic dogs in Italy. Vet Diseases. St Louis, MO: Elsevier, 2014, pp. 141–51.
Microbiol 2013; 166: 246–9. Venn EC, Preisner K, Boscan PL, Twedt DC, Sullivan LA.
Hernández‐Blanco B, Catala‐López F. Are licensed canine Evaluation of an outpatient protocol in the treatment of
parvovirus (CPV2 and CPV2b) vaccines able to elicit canine parvoviral enteritis. J Vet Emerg Crit Care 2017;
protection against CPV2c subtype in puppies? A 27: 52–65.