Page 244 - Veterinary Immunology, 10th Edition
P. 244
factors can trigger cell differentiation. This is especially important
VetBooks.ir in the T cell system, where the cells are plastic and can readily
transform from one subset to another. These transcription factors
include T-bet, which controls transcription of IFN-γ in Th1 cells;
GATA3, which controls cytokine transcription in Th2 cells; ROR γT,
which acts in Th17 cells; and FoxP3, which acts in Treg cells.
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