Page 326 - Veterinary Immunology, 10th Edition

Lymphocyte Circulation, 117
VetBooks.ir Species Differences, 117

Hemolymph Nodes, 118

Spleen, 118

Structure of White Pulp, 118

Function, 119

Other Secondary Lymphoid Organs, 120

Tertiary Lymphoid Organs, 121

LEARNING OBJECTIVES

After reading this chapter, you should be able to:

• Understand that adaptive immunity is mediated by cells called lymphocytes
found mainly within lymphoid organs.

• Recognize that lymphocytes arise from lymphoid stem cells in the bone marrow.
• Understand the different roles of primary and secondary lymphoid organs.
• Understand and explain the functions of the primary lymphoid organs.

• Describe the structure and development of the thymus and understand that T
cells mature within the thymus.

• Describe the structure and function of the bursa of Fabricius.
• Explain the different effects of neonatal and adult thymectomy.
• Describe how B cells mature within gastrointestinal lymphoid tissues, the bone
marrow, or the bursa of Fabricius.

• Understand why, if newly developed lymphocytes have receptors that can bind
self-antigens, they are killed before they can leave primary lymphoid organs.

• Understand the functions of the secondary lymphoid organs, the lymph nodes,
and spleen.
• Describe the structure of lymph nodes and the spleen.
• Describe the circulation of lymphocytes.

• Understand the different functions of ileocecal and jejunal Peyer's patches.

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