Page 327 - Veterinary Immunology, 10th Edition

• Define red pulp, white pulp, germinal center, high endothelial venule, Peyer's
VetBooks.ir patch, Hassall's corpuscles, and tertiary lymphoid organ.

Although antigens are trapped and processed by dendritic cells,
macrophages, and B cells, adaptive immune responses are actually

mounted by cells called lymphocytes. Lymphocytes are the small
unspectacular round cells that predominate in organs such as the
spleen, lymph nodes, and thymus (Fig. 12.1). These are called
lymphoid organs. Lymphocytes have antigen receptors on their

surface and can recognize and respond to foreign antigens.
Lymphocytes are eventually responsible for the production of
antibodies and for cell-mediated immune responses. The lymphoid
organs must therefore provide an environment for efficient

interaction among lymphocytes, antigen-presenting cells, and
foreign antigens, as well as sites where lymphocytes can respond
optimally to processed antigens.

FIG. 12.1 The major lymphoid tissues of the pig, a typical
mammal.

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