Page 371 - Veterinary Immunology, 10th Edition

Dogs 46-72 j 7-30 j 27-33 i j 17-18 j i 1.7 i j
VetBooks.ir a Park YH, Fox LK, Hamilton MJ, Davis WC: Bovine mononuclear leukocyte subpopulations
Cats
6-39
6-50
1.9
19-49
31-89
k
k
k
1.9-2.4
10-15
Humans 70-75
43-48
22-24
in peripheral blood and mammary gland secretions during lactation, J Dairy Sci 75:998-
1006, 1992.
b Thorp BH, Seneque S, Staute K, Kimpton WG: Characterization and distribution of
lymphocyte subsets in sheep hemal nodes, Dev Comp Immunol 15:393-400, 1991.
c Smith HE, Jacobs RM, Smith C: Flow cytometric analysis of ovine peripheral blood
lymphocytes, Can J Vet Res 58:152-155, 1994.
d + +
Pescovitz MD, Sakopoulos AB, Gaddy JA, et al: Porcine peripheral blood CD4 /CD8 dual
expressing T-cells, Vet Immunol Immunopathol 43:53-62, 1994.
Saalmüller A, Bryant J: Characteristics of porcine T lymphocytes and T-cell lines, Vet
e
Immunol Immunopathol 43:45-52, 1994.
f
Joling P, Bianchi AT, Kappe AL, Zwart RJ: Distribution of lymphocyte subpopulations in
thymus, spleen, and peripheral blood of specific pathogen free pigs from 1 to 40 weeks of
age, Vet Immunol Immunopathol 40:105-118, 1994.
g McGorum BC, Dixon PM, Halliwell RE: Phenotypic analysis of peripheral blood and
bronchoalveolar lavage fluid lymphocytes in control and chronic obstructive pulmonary
disease affected horses, before and after “natural (hay and straw) challenges,”Vet
Immunol Immunopathol 36:207-222, 1993.
h
Grunig G, Barbis DP, Zhang CH, et al: Correlation between monoclonal antibody reactivity
and expression of CD4 and CD8 alpha genes in the horse, Vet Immunol Immunopathol
42:61-69, 1994.
i Rivas AL, Kimball ES, Quimby FW, Gebhard D: Functional and phenotypic analysis of in
vitro stimulated canine peripheral blood mononuclear cells, Vet Immunol Immunopathol
45:55-71, 1995.

j
Walker R, Malik R, Canfield PJ: Analysis of leucocytes and lymphocyte subsets in cats
with naturally-occurring cryptococcosis but differing feline immunodeficiency virus status,
Aust Vet J 72:93-97, 1995.
k
Bleavins MR, Brott DA, Alvey JD, de la Iglesia FA: Flow cytometric characterization of
lymphocyte subpopulations in the cynomolgus monkey (Macaca fascicularis), Vet Immunol
Immunopathol 37:1-13, 1993.

Similar experiments involving bursectomy in chickens pointed to
the existence of B cells. In mammals, B cells originate in the bone
marrow but mature within Peyer's patches or the bone marrow
before migrating to the secondary lymphoid organs. B cells

predominate in the cortex of lymph nodes, in follicles within the
Peyer's patches and spleen, and in the marginal zone of the white
pulp of the spleen. B cells account for 10% to 40% of blood
lymphocytes (see Table 13.2).

Natural killer (NK) cells, a population of innate lymphoid cells,
were identified as a result of the detection of cytotoxic lymphocytes

371