Page 500 - Veterinary Immunology, 10th Edition

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FIG. 16.16 The unusual variable regions of the bovine IgM with a
stem and knob structure

FIG. 16.17 A ribbon diagram showing the structure of a bovine
Fab (left) as compared to a “normal” Fab showing the superlong β-
stranded stalk protruding from the VH immunoglobulin domain. (From
Wang F, Ekiert DC, Ahmed I, et al: Reshaping antibody diversity, Cell, 153: 1379-
1393, 2013, Courtesy Elsevier Inc.)

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