Page 606 - Veterinary Immunology, 10th Edition
P. 606

Transforming Growth Factor-β, 215
  VetBooks.ir    Regulation by the Innate Immune System, 216



                         Th17 Cells, 216


                         Interleukin-17, 216


                         Regulatory Macrophages, 218

                         Indoleamine 2,3-Dioxygenase and

                         Tolerance, 218


                         Tolerogenic Dendritic Cells, 218


                         Regulatory B Cells, 218


                         Natural Suppressor Cells, 218

                         When Do Regulatory Cells Work?, 218


                 Regulation of Apoptosis, 218

                 Neural Regulation of Immunity, 219

                         Stress, 219

                         Autonomic Nervous System, 220


                         Hypothalamic-Pituitary-Adrenal Cortical

                         Axis, 220


                         Neuropeptides and Lymphocytes, 220








               LEARNING OBJECTIVES




                 After reading this chapter, you should be able to:
                 • Explain how and why T cells do not respond to normal body components.

                 • Define negative selection, positive selection, clonal anergy, and immunological
                   tolerance and differentiate between central and peripheral tolerance.
                 • Understand why B cells are much harder to tolerize than T cells.




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