Page 461 - The Veterinary Care of the Horse
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intramedullary  infusion  reach  higher  tissue  concentrations  than  can  be  achieved  by

             systemic dosing.
  VetBooks.ir  •  Non-steroidal anti-inflammatory drugs to reduce the associated pain and inflammation

             may be helpful in adult horses, but are used with caution in foals due to the risk of gastric
             ulceration.



        PROGNOSIS

        The prognosis is generally guarded. It depends on the severity and location of the infection
        and how well established it is.





        BONE CYSTS



        Bone cysts (known as osseous cyst-like lesions [OCLLs] or subchondral bone cysts [SBCs]
        are round or oval-shaped cystic lesions that usually occur in the subchondral bone, directly

        beneath the articular cartilage of a joint. Cysts that develop in young animals that are still
        growing often migrate away from the joint surface as the skeleton matures.

             They can occur in horses of any age but are often found in young animals less than 4
        years old. The most common sites are the stifle, fetlock, pastern, coffin and elbow joints.



        Causes


        The exact cause of these lesions is unclear. They can develop wherever there is a defect in the
        articular cartilage or subchondral bone. This may be the result of trauma or a developmental

        defect  such  as  osteochondrosis  (see  page  242).  In  some  cases,  a  number  of  factors  may
        contribute to their development.



        Pathophysiology


        Synovial fluid is thought to flow through cracks in the damaged articular cartilage into the
        subchondral bone. Mechanical factors, including weight bearing, then lead to resorption of

        bone and the formation of a cyst-like structure.



        Clinical signs


        •    Mild to moderate lameness that may be sudden in onset.
        •    The lameness may be intermittent and improve with rest.
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