Page 649 - The Veterinary Care of the Horse
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body secretions. Once a stallion has been infected, he may continue to shed the virus in his

        semen  for  weeks,  months  or  the  rest  of  his  life.  His  fertility  is  not  affected  once  he  has
  VetBooks.ir  recovered from the early stage of the disease. If he infects mares during mating, they may
        then spread the virus via the respiratory route. Infected mares and geldings become free of

        the virus after a few weeks and do not become chronic ‘shedders’ of the virus.



        Diagnosis


        It is not always possible to identify the disease from the clinical signs, so laboratory tests are
        essential. The diagnosis is made by detecting the virus (virus isolation test) in:
        •    nasopharyngeal swabs

        •    blood

        •    semen

        •    urine

        •    the tissues and fluids from the placenta and aborted foetuses.



        Blood  is  also  tested  for  antibodies  to  the  virus.  If  there  are  no  antibodies,  the  horse  is

        seronegative. If antibodies to equine arteritis virus are present, it is seropositive. If rising
        levels of antibodies are seen in consecutive samples, this indicates recent infection.

             Characteristic changes are seen in infected foetal tissues such as lymph nodes, spleen,
        lung and liver when they are examined under the microscope.



        Treatment


        As with most viruses there is no specific medical treatment available and none is usually
        necessary  apart  from  general  nursing.  Non-steroidal  anti-inflammatory  drugs  may  help  to

        bring  down  the  horse’s  temperature  and  alleviate  some  of  the  discomfort  caused  by  the
        disease.



        Vaccination


        A  vaccine  (Artervac)  is  available  for  protection  against  equine  arteritis  virus.  The  initial
        course consists of two injections given 3–6 weeks apart from the age of 9 months. Boosters

        are  given  every  6  months.  In  the  UK,  stallions  and  teasers  are  vaccinated  annually.  The
        vaccine is not given to mares.

             All  vaccinated  horses  become  seropositive  and  it  is  not  possible  to  determine  from  a
        blood test whether the antibodies are due to the vaccination or to infection. This information
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