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                            An Overview of Gastrointestinal Cancers in India




             Dr. Nazir Ahmad Khan
             Department Of Radiation Oncology
             Sheri Kashmir Institute of Medical Sciences Srinagar


             Contributing Authors Affiliations:
             N/A

       Diagnosis of cancer has always brought in its wake feelings of misery, pain and helplessness. Heavy and often futile
       expenditure. Diagnosis of cancers is considered to be one of the most feared diagnosis because despite advances in
       technology and treatment, cancer is still thought to be life altering event. But it should not be forgotten that 2/3rd (70%)

       of cancer burden is related to life style factors hence preventable. 1/3rd cancers (2 out of 5) are tobacco related and
       others due to faulty diet habits and social habits .
       Gastrointestinal cancers refers to malignant conditions of the gastrointestinal tract and accessory organs of digestions

       including the esophagus, stomach, biliary system , pancreas, small intestine, large intestine, rectum and anus. Cancer
       of GI tract is one of the most common cause of cancer related death in India.  Gastrointestinal cancers is the most
       common form of cancer worldwide and continue to be among the top ten cancers in most of the parts of the country.

       The most prevalent of GI cancers is colorectal cancer in the western world and gastric cancers in the eastern world. In
       India esophageal cancer is highest in north eastern states. Gastric cancer is also common in north east and southern
       states  of  Indian  subcontinent  .Gallbladder  cancer  is  more  common  in  northern  India  while  as  rectal  cancer  in

       southerner India. Pancreatic cancer is low in India while as anal canal cancer is very rare.
       Our patients with cancer generally have a poor prognosis, because of low awareness about symptoms, and treatment
       .Patients usually present to doctor late. Symptoms of GI cancer vary depending on the type of cancer that may include

       difficulty in swallowing, abdomen pain and discomfort, change in bowel habits, rectal bleeding, bloating, loss of
       appetite, nausea, vomiting, unusual weight loss, fatigue. The risk factors for various types of GI cancers include
       smoking, alcohol consumption, high animal fat diet, high amount of salt intake, spicy diet, pickels, obesity, chronic

       pancreatitis.
       The lack of access to affordable curative services and the late diagnosis result into poor outcome of treatment. GI
       cancers are complex diseases, each patient's cancer is different, behaving differently in the bodies they are in, and

       thus need a tailored individual's treatment plan. Treatment for GI cancer will depend on the type of cancer, the stage or
       its  development,  performance  status,  comorbidity  conditions  etc.  Treatment  commonly  includes  Surgery,
       Chemotherapy and Radiation therapy.

       Positive way forward should be to have multicentric randomized trials in GI cancers to have more robust inference,
       which can be applied specifically to our population.



             Corresponding Author
             Dr. Nazir Ahmad Khan
             Department Of Radiation Oncology
             Sheri Kashmir Institute of Medical Sciences Srinagar








                         The Integrated Indian Journal of Cancer Sciences
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