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© 2019 ASPEN | American Society for Parenteral and Enteral Nutrition. All Rights Reserved.  Evidence of PN Use to Treat Malnutrition

                                                                                            Pre-operative PN

                                                                                            • No difference

                                                                                                 o Baseline Clinical and laboratory characteristics
                                                                                                 o Postoperative complications
                                                                                                 o Outcome parameters

                                                                                                        - Infectious complications
                                                                                                        - Morbidity
                                                                                                        - Mortality
                                                                                                        - Hospital stay

                                                                                            • Evidence of comparable PN outcomes with EN in MN cancer patients

                                                                                            Klek S et al Clin Nutr 30:708, 2011

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                                                                                            Evidence of PN Use to Improve Lean Body Mass

© 2019 ASPEN | American Society for Parenteral and Enteral Nutrition. All Rights Reserved.  Long Term PN in Pancreatic Cancer

                                                                                            • N = 32, 18 (8-35) weeks
                                                                                            • Advanced pancreatic cancer and cachexia

                                                                                                o Excessive weight loss despite additional enteral nutrition support

                                                                                            • BIA method

                                                                                                o Phase angle
                                                                                                o ECM/BCM index
                                                                                                o BMI

                                                                                            ECM/BCM – extracellular mass/body cell mass
                                                                                            Pelzer U et al. BMC Cancer !0:86, 2010

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