Page 23 - Avoid Food and Drug Interactions

Hyperglycemia in PN patients1,2

Criteria N (%) Comment NSS

> 200 mg/dl 0 (0) -Dext infusion < 4 mg/kg/min Yes, dextrose-based diet
5 (7) -Dext infusion 4-5 mg/kg/min
© 2019 ASPEN | American Society for Parenteral and Enteral Nutrition. All Rights Reserved. 18 (43) -Dext infusion >5 mg/kg/min
No risk factors present

>200 mg/dl 22 (44) Resulted in 1.4 events per patient Yes, pharmacist management
>150 mg/dl 45 (90) course

Risk factors: diabetes, pancreatitis,
Steroids

• Use daily ILE to reduce dextrose dose in PN

o If only use ILE for EFAD prevention, dextrose infusion rate is 4 mg/kg/min when
providing 28 Cal/kg/d and 1.5 g Protein/kg/d

• Establish a target glucose: 140-180 mg/dL

1Rosmarin et al, NCP 1995
2Pleva et al, NCP 2009

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© 2019 ASPEN | American Society for Parenteral and Enteral Nutrition. All Rights Reserved. Learning Assessment Question 3

(True or False) There is a relationship between elevated
glucose (hyperglycemia) and poor outcomes in parenteral
nutrition patients.
A.True
B.False

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