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124 4.4  Preterm Infants

Table 4.4.3  Feeding routes for preterm infants

                   Route                     Feeds used

Parenteral         Administered directly     A sterile complete feed delivered     Infants who are born at
nutrition          into the bloodstream      as an aqueous solution with a         <1000 g, and some <1500 g
                   usually via peripherally  standardized composition of           Some intrauterine growth
Enteral nutrition  sited central venous      dextrose, amino acids, electrolytes,  restriction infants
                   access                    vitamins and minerals. Alongside
Breastfeeding                                this, a lipid solution containing     Begin as soon as clinically
Bottlefeeding      Milk feed via a           fat-soluble vitamins is also infused  indicated as trophic
                   nasogastric (NG) tube                                           feeding (minimal enteral
                   (from nose to stomach)    In order of preference:               feeding) and increase as
                   or an orogastric tube     Expressed breast milk (EBM)           tolerated
                   (mouth to stomach)        Banked expressed breast milk
                                             (BEBM)                                Can begin when infant
                   Oral feeding direct       Breast milk fortifiers may be added   starts to coordinate suck,
                   from the mother’s         to either EBM or BEBM                 swallow and breathing for
                   breast                    Preterm formula                       short periods
                   Oral feeding using
                   sterilized bottles and    Breast milk
                   teats
                                             Expressed breast milk
                                             Preterm formula
                                             Nutrient-enriched post-discharge
                                             formula

Parenteral nutrition (Figure 4.4.2)                      neonatal unit will have nutrient requirements for
                                                         growth as described in Table 4.4.4 (Tsang et al.
Parenteral nutrition has been used in neonatal           2005, ESPGHAN Committee on Nutrition 2010).
units for many decades to feed infants born too
early to tolerate an adequate amount of enteral          Enteral nutrition
feeds. It is now common practice on neonatal units.
There is no consensus on which babies should             Enteral nutrition is used for infants with:
receive parenteral nutrition but it is mainly used for
the following groups of infants:                         ●● immature suck/swallow
                                                         ●● mechanical ventilation with an endotracheal
●● those with a birthweight less than 1250  g, as
   studies have shown that they can take up to              tube in place preventing oral feeding
   four weeks to establish full enteral feeds            ●● limited oral intake that is less than adequate and

●● infants <30 weeks gestation                              requires top-up of feeds via a nasogastric or
                                                            orogastric tube (see Figure 4.4.2).
●● where there is a non-functioning gastrointestinal
   system either pre or post operation                   The route of the tube will depend on how the baby
                                                         is receiving ventilation or oxygen support.
●● those with short bowel syndrome.
                                                         Trophic feeds or minimal enteral
Some parenteral nutritional requirements are             feeding
lower than those for enteral and oral nutrition
because absorption across the gut wall is not            Trophic feeds or minimal enteral feeding is often
complete. Most stable preterm infants on a               used in neonatal units, especially for the smallest
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