Page 128 - Medicinal Chemistry Self Assessment
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Section 3 General Self Assessment Answers
2.6 Stereochemistry and Drug Action
2.6
Stereochemistry and Drug Action
1. Shown below are the structures of acebutolol, estradiol, cefamandole, and nifedipine. For each of these
1. Shown below are the structures of acebutolol, estradiol, cefamandole, and nifedipine. For each of these
compounds, identify all chiral centers.
compounds, identify all chiral centers.
N OH
O O
OH
H N H O
Estradiol
O
Acebutolol
H
H 3 C N CH 3
O
S H 3 CO 2 C
N CH 3 CO 2 CH 3
H
OH N S N NO 2
O N
CO 2 H N N
Cefamandole Nifedipine
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