Page 183 - PG 101-Course notes مذكرة النظري 24-25 with spec

Medicinal plants (PG 101) Level 1 Clinical Pharmacy-PharmD

Enzyme Inhibitors

There are two types of inhibitors:

1- Specific or competitive 2- Non-specific (Non-competitive)

inhibitors inhibitors

These inhibitors are substances These substances block the action of

having molecular structure imitating many enzymes by blocking or
that of substrate, so they are reacting with some active groups in

reversibly block the enzyme active the protein molecular structure of the
centers by forming enzyme enzyme as C=O, -SH, -NH2 groups.

inhibitor complex Such inhibitors are ion of metals
2+
2+
2+
like Cu , Zn , Hg .
.

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