Page 217 - Pharmacognosy 2 PG303
P. 217

Pharmacognosy-2 (PG303)                              Level 2                Clinical Pharmacy-Pharm D


              Constituents
                     It contains 1.8-4% alkaloids, especially emetine and cephaline. their  1',2'-
              dehydro-derivatives psychotrine, O-methyl psychotrine,, and other minor alkaloids.
              The ratio emetine: cephaline is 2:1 to 3:1 for the Rio drug and 1:1 to 3:,2 for the
              Cartagenna drug. Contrary to older reports, saponins are absent, and the supposed
              "ipecacuanhin", "ipecacanhic acid", and "saponin of ipeca" are crude mixtures of
              ipecoside, a tetrahydro-isoquinoline monoterpenoid glycoside, and sucrose. Other
              such N-containing glycosides are present and also the iridoids sweroside and 7-
              dehydro-loganin.
























































                                                             Ipeca
                                                                                                     X 300

                   1- Parenchymatous cells of the               7- Part of a group of
                   phelloderm showing a bundle of                 tracheids.



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