Page 236 - Pharmacognosy 2 PG303
P. 236

Pharmacognosy-2 (PG303)                              Level 2                Clinical Pharmacy-Pharm D

                     It is native in North-western China and Tibet, cultivated to some extent
              in Europe. The drug is imported from China and India; Pakistan also supplies
              rhubarb, which mostly doesn't meet pharmacopeial standards.

              Macroscopical Characters
                     The  drug  consists  of  peeled  underground  organs  (turnip-shaped roots
              with  very  small  rhizomes).  The  ochre-yellow  to  brownish  pieces  are  often
              covered on the outside with powder and they exhibit orange striations or an
              orange-red mottling. The fracture is granular and crumbly (not fibrous) and
              reddish brown; Odor: characteristic and faintly smoky. Taste: somewhat bitter
              and harsh and slightly astringent. It is very gritty between the teeth and colors
              the saliva yellow.






























                     Chinese  rhubarb.  Shensi;  A.  Shensi  flat.  B,  Shensi  round.  C.  end  of
                     Shensi round. D. detail of the reticulation. h, hole with embedded string;
                     k, knife-mark; l.s.p., star spot cut longitudinally; m.r., medullary ray; r,
                     reticulation; s, starchy parenchyma; s.p.,star-spot.

                     Rhubarb occurs in sub-cylindrical, barrel-shaped, conical, plano-convex,
              or rectangular pieces, each occasionally; showing a perforation; 5-17 cm long,
              4-10 cm wide. Externally, it is usually dusted with a fine bright, brownish yellow
              powder and showing longitudinal reddish-brown lines and dots, embedded in a
              grayish white ground tissue. This. frequently forms a network of whitish lines,
              in the rneshess of which are alternating white phloem parenchyma, and orange
              or brownish red lines, the medullary rays, and occasional star spots and rarely
              small patches of brown  cork. The  pieces are compact,  firm,  hard and heavy.
              Fracture, granular and uneven. Internally, it is pinkish brown to grayish, not
              discolored or lacunous. It shows numerous reddish-brown lines, embedded in



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