Page 313 - Pharmacognosy 2 PG303
P. 313

Pharmacognosy-2 (PG303)                              Level 2                Clinical Pharmacy-Pharm D

                 of chondrin is indicated also by the solubility of gelatin in acetic acid and by its
                 failure to produce a precipitate with alum T.S., solution of lead acetate, ferric
                 chloride T.S., copper acetate T.S., or mercuric chloride T.S.  Gelatin should be
                 also free from albumin where no black precipitate is formed with lead acetate
                 solution.
              2-  Millon’s reagent test:  To an aqueous solution of Gelatine, add Millon’s reagent;
                 a white precipitate is formed, becoming brick-red on warming.
              3-  Soda lime test:  Heat Gelatine with soda lime; ammonia gas is evolved.

               Constituents
                     Gelatine consists chiefly of the protein glutin. It responds to the usual tests
              for proteins.

              Uses
                     Apart from its various technical uses, gelatine has been employed as a nutrient
              and as a styptic, but its value for these purposes has been over-rated.  It is also used
              as a basis for glycerine suppositories, for the preparation of pastilles and for the
              preparation  of  nutrient  media  for  the  growth  of  bacteria,  some  of  which  cause
              liquefaction of the medium.



                                                        Gambir


                         Syn.:  Pale Catechu; Catechu; Gambier; Terra Japonica; Gambir-Katechu.

                     Gambir is the dried aqueous extract prepared from the leaves and twigs of
              Uncaria Gambier (Hunter) Roxb. (Fam. Rubiaceae).

                     The  plant  is  a  climbing  shrub  indigenous  to  the  Malay  Archi-pelago  and
              largely cultivated on the small islands between Singapore and Sumatra, and on other
              islands of the Archipelago.

              Preparation
                     When the plants are about 8 years old, the shoots are cut down and the young
              leafy plants are thrown into a specially constructed container, three-quarters full of
              boiling water.  The contents are boiled for about 3 hrs; being stirred and bruised with
              a four-pronged wooden fork.  The marc is finally removed by wooden forks having
              three large flat prongs and is thrown on to a sloping trough about 6 metres long and
              projecting over the edge of the container so that the liquor may drain back into it,
              the marc is washed with a little water and is pressed in the trough.  The decoction is
              evaporated for about 1.5 hrs till it turns yellowish-green, thick, and pasty.  It is then




                                                            255
   308   309   310   311   312   313   314   315   316   317   318