Page 318 - Pharmacognosy 2 PG303
P. 318

Pharmacognosy-2 (PG303)                              Level 2                Clinical Pharmacy-Pharm D

                 faintly with HCl and add few drops of FeCl 3 T.S.; a brown red to purplish-red
                 color is produced.  This color is not destroyed by dilute HCl or by HgCl 2 T.S.
                 (c.f. Thiocyanates).





















                   Fragments  of  the  capsule  wall  of  Fragments of the foliage leaf of

                   Papaver somniferum:                            Papaver somniferum:
                   A,  outer  ep.;  B,  outer  ep.  from  the  A, T.S. of the lamina.
                   stigma; C, inner ep. of the capsule wall;  B, upper ep.;
                   D, T.S. of the inner ep. of the capsule  C, lower ep.
                   wall;  E,  T.S.  of  the  inner  ep.  of  the
                   capsule wall; F, pollen grains.
                                          Vegetable debris of raw opium

              Constituents
                     Opium contains more than 25 alkaloids; the most important of which  are:
              morphine (4-21 %); codeine (0.8-2.5 %); noscapine (formerly narcotine, 4-8 %),
              papaverine,  thebaine,  narceine,  neopine, protopine,  laudanine,  and  laudanosine...
              etc.    Opium  also  contains  from  3-5  %  of  meconic  acid  which  exists  free  or  in
              combination with morphine, codeine, and other alkaloids.

              Uses
                     Opium acts chiefly upon the central nervous system; producing stimulation
              followed by depression.  It is a potent analgesic, hypnotic and narcotic drug.  Opium
              abuse  produces  severe  physical  dependence.    It  is  one  of  the  opiates  under
              international control.  Medicinally, opium is used as a source for morphine (anal-
              gesic), codeine (cough sedative) and papaverine (antispasmodic for smooth muscle).
                                                   DRIED JUICES

                     Juices  are  fluid  plant  saps;  being  usually  aqueous  liquids,  containing
              dissolved substances and are usually present in plants in special structures.  They
              occur either in cells, e.g., Aloes and Kino or in cavities, e.g., Eucalyptus …etc.  The






                                                            260
   313   314   315   316   317   318   319   320   321   322   323