Page 323 - Pharmacognosy 2 PG303
P. 323

Pharmacognosy-2 (PG303)                              Level 2                Clinical Pharmacy-Pharm D

                     This group includes Resins (e.g., Colophony, Guaiacum, Jalap, Podophyllum,
              and Scammony resins), Gum-Resins (e.g. Gamboge), Oleo-Resins (e.g. Copaiba,
              and  Male  fern),  Oleo-Gum-Resins  (e.g.  Myrrh,  Asafoetida,  Galbanum,
              Ammoniacum, Olibanum and Mastic) and Balsams (e.g. Benzoin, Peru, Tolu and
              Storax).

              RESINS

                     Resins are hard, solid, or semisolid amorphous organic substance of complex
              nature.  They are insoluble in water, mostly insoluble in petroleum ether, but dissolve
              more or less completely in alcohol, chloroform and ether, forming solutions which
              on evaporation, deposit the resin as a varnish-like film.  They are also soluble in
              many  other  organic  solvents  as  well  as  in  fixed  and  volatile  oils  and  in  chloral
              hydrate.  Resins, on heating soften and finally melt.  They burn with smoky flame.

                     Resins  are  obtained  mainly  by  incision  or  by  extraction  with  ethanol  and
              precipitation in water or by other methods.

                     Resins occur in plants either alone as in Guaiacum, or commonly associated
              with volatile oils as in oleoresins e.g. Terpentine, Copaiba etc., or with gums as in
              gum-resins e.g. Gamboge, or with gums and volatile oils as in oleo-gum resins e.g.
              Myrrh,  Asafoetida.    Resins  are  found  either  in  all  elements  of  the  drug  e.g.,
              Guaiacum resin, being present in all elements of Guaiacum wood or commonly in
              special structures, i.e. in special cells, ducts, cavities or external gands.

                     Several resins are used in medicine. The following ones are official in the
              Egyptian Pharmacopoeia:  Resina Terebinthinae, Resina Guaiaci, Resina jalapoe,
              Resina Podophylli, and Resina Scammonioe.

                                                      Colophony

              Syn.:  Colophonium; Resina Terebinthinae; Resina Colophonium Gallicum; Rosin.

                     Colophony is the residue left after distilling the volatile oil from the oleo-resin
              obtained from Pinus palustris Mill., P. toeda L. and other species of Pinus (Fam.
              Pinaceae).

















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