Page 322 - Pharmacognosy 2 PG303
P. 322

Pharmacognosy-2 (PG303)                              Level 2                Clinical Pharmacy-Pharm D


                                                             Kino

              Syn.:  East Indian, Malabar, Madras or Cochin Kino

                     Malabar  Kino  is  the  dried  juice  obtained  from  incisions  in  the  trunk  of
              Pterocarpus marsupium Roxb., (Fam. Leguminosae).  The tree grows in southern
              India and Ceylon.

              Preparation
                     The  phloem  of  the  tree  contains  numerous,  comparatively  wide  and  short
              tubular cells arranged in axial rows.  These cells are filled with a red astringent fluid,
              which flows from them when they are wounded.  The juice that flows is collected in
              small cups made of leaves, or in other convenient receptacles, and soon dries in the
              sun to a dark mass.  It is sometimes boiled before it is evaporated.

              Description
                     Kino occurs in small glistening angular grains appear quite black and are
              remarkably free from dust.  The grains are about 3-5 mm in diameter.  When the
              edges of the grains are examined, they are seen to be transparent and of a dark ruby-
              red colour.  They are hard and brittle, breaking with a vitreous fracture and yielding
              a brownish-red powder.  Kino is odourless, but has, when chewed, an astringent
              taste, and adheres to the teeth colouring the saliva red.

              Solubility
                     In cold water, Kino is only partially soluble (from 80-90 %).  It dissolves to a
              greater extent in hot water and is almost entirely soluble in alcohol 90 %.

              Tests for Identity
                     The aqueous solution turns green on the addition of a ferrous salt, violet with
              an alkali, and gives a precipitate of Kinotannic acid when acidified with a mineral
              acid.

              Constituents
                     Kino contains kinotannic acid (30-80%); kinoin (1.5 %); catechol; kino-red;
              gallic acid; resin; gum; pectin; and an oxidase enzyme.

              Uses
                     Kino  is  a  powerful  astringent.    It  is  given  internally  for  diarrhoea  and
              dysentery and is also used externally.

                                    RESINS AND RESIN COMBINATIONS





                                                            264
   317   318   319   320   321   322   323   324   325   326   327