Page 151 - Pharmacognosy 2 PG303
P. 151
Level 2 Clinical Pharmacy-Pharm D
Ephedra Ergot
(Ma Hung)
Dried sclerotium of the fungus, Claviceps
wigs of Ephedra sinica Family: purpurea (family: Hypocreaceae), developed
eae in the ovary of rye plant, Secale cereale
(family: Gramineae).
ds: Ephedrine, Pseudoephedrine. Alkaloids: Ergotamine, Ergometrine,
Ergotoxine.
hmatic drug: nasal decongestant, 1. Ergometrine: control uterine hemorrhage in
odilator.
ect: headache, nausea, and vomiting. childbirth. (Postpartum bleeding).
indication: heart conditions and 2. Ergotamine: in treating migraine.
nsion.
Test for ergotoxine:
dosages: increased blood pressure p- dimethyl amino benzaldehyde (freshly
diac rhythm disorders. prepared) + FeCl3 in H2SO4,
A blue color is produced.
1- In humans: (Ergotism) convulsions and
gangrene of hands and feet.
2- In cattle: develop a gangrene of ears, tails
and hoofs, pregnant cows also become aborted
and may die.
Shape: fusiform
Odor: disagreeable
Taste: oily, disagreeable
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