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tHe SCieNCe   beHiNd tHe StOry





                     Measuring the                                                        children from 39 Mexico City schools
                     Health impacts of                                                    across 3 years and correlated this
                                                                                          with their exposure to tropospheric
                     Mexico City’s                                                        ozone, nitrogen dioxide, and par-
                     Air Pollution                                                        ticulate matter. The children’s ability to
                                                                                          inhale and exhale deeply improved as
                     “I know I’m inhaling poison,” a 38-year-                             they matured, but children from more
                     old candy vendor named Guadalupe                                     polluted areas lagged behind those
                     told a reporter amid the fumes of a                                  from cleaner areas, indicating smaller,
                     traffic-choked intersection in Mexico                                weaker lungs.
                     City. “But there is nothing I can do.”  Dr. Lilian Calderón-garcidueñas  Romieu and her colleagues also
                        For as long as we have polluted                                   showed in a series of studies that the
                     our air, people have felt effects on their                           city’s pollution worsens asthma in
                     health. But identifying and quantify-  of tropospheric ozone formed in smog   children, particularly those with certain
                     ing those impacts poses a challenge   (not nitrogen oxides, as was expected).   genetic profiles. In 2008 her team
                     for scientists. For researchers want-  City officials responded by targeting   analyzed data from 200 asthmatic and
                     ing to understand pollution’s health   VOC emissions for reduction.  healthy children and found that children
                     impacts—and design solutions for      Few people today understand    in areas with more traffic and pollutants
                     people like Guadalupe—what better   Mexico City’s air pollution in more   coughed, wheezed, and used medica-
                     place to go than Mexico City, long   detail than Armando Retama, the city’s   tion more often.
                     home to some of the world’s worst air   director of atmospheric monitoring. But   Another Mexican researcher, Lilian
                     pollution?                        he may grasp its impacts best when   Calderón-Garcidueñas, has led several
                        A key first step is to deter-  he leaves town. “I can breathe better.   studies comparing chest X-ray films
                     mine what’s actually in the air. One   I’m not all dry. My eyes aren’t irritated.   and medical records of Mexico City
                     researcher who has led the way is   My skin doesn’t crack,” he says. “We   children with those of similar children
                     Mario Molina, the Nobel Prize–winning   have chronic symptoms that we aren’t   from nonpolluted locations. Her team
                     chemist who helped discover the   aware of.”                         found hyperinflation and other problems
                     cause of stratospheric ozone deple-   Most health impacts of urban   with the lungs of the Mexico City youth.
                     tion and who appears in this chapter’s   pollution affect the respiratory system.   Mexico City children also reported
                     other Science behind the Story    At high altitudes like Mexico City’s,   many respiratory problems whereas
                     feature (pp. 488–489). Molina stepped   the “thin air” forces people to breathe   rural children did not (Figure 1).
                     away from scholarly work at U.S.   deeply to obtain enough oxygen.      Air pollution harms the heart
                     universities to return to his hometown   This means they pull more air pollut-  and the cardiovascular system, too.
                     of Mexico City and help address its   ants into their lungs than people at   Multiple recent studies reveal that
                     pollution issues. Here, in 2003 and   lower elevations. As result, respiratory   pollution can affect heart rate, blood
                     2006, Molina organized intensive air-  problems are commonplace. Many   pressure, blood clotting, blood vessels,
                     sampling projects involving hundreds   studies have confirmed that Mexico   and atherosclerosis. Epidemiological
                     of scientists.                    City residents show reduced lung   studies (pp. 393–394) show that pol-
                        Nearly 200 research publications   function in comparison with people   lution correlates with emergency room
                     later, these efforts have clarified many   from less-polluted areas and that res-  admissions for heart attacks, chest
                     aspects of the city’s pollution. For   piratory problems become worse and   pain, and heart failure, as well as death
                     instance, one study used machines   emergency room visits become more   from heart-related causes.
                     that could identify and record individual   numerous when pollution is severe.  Part of the reason smog impacts
                     particles in real time, and found that   Most studies have looked at   the cardiovascular system is that
                     metal-rich particulates from trash incin-  short-term exposure, but in 2007 a   tiny particulates can work their way
                     erators were peaking in the morning,   research team led by Isabelle Romieu   into the bloodstream, causing the
                     whereas smoke from fires outside the   of Mexico’s National Institute of Public   heart to reduce blood flow or go out
                     city blew in during the afternoon. Other   Health examined the effects of growing   of rhythm. Even young people are
                     researchers discovered that volatile   up amid polluted air. Her team meas-  at risk. One Mexican research team
                     organic compounds control the amount   ured lung function in 3170 8-year-old   analyzed the hearts of 21 people from




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           M17_WITH7428_05_SE_C17.indd   484                                                                                    12/12/14   3:22 PM
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