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7–8 from Mexico City with 10 simi-
                            Cough                                                               20%
                                                           lar children from a Mexican city with
                             Nasal                         clean air, measuring their cognitive
                         obstruction                       skills and scanning their brains with   15%
                             Nasal                         magnetic resonance imagery (MRI).
                           dryness                                                              10%
                                                           Results showed that the Mexico City   Percent change in likelihood of death
                             Chest                         children performed more poorly on
                         discomfort                        most cognitive tests of reasoning,    5%
                             Nasal                         knowledge, and memory. The differ-
                            lesions                                                              0%
                                                           ences in cognition were consistent
                          Scabbing                         with differences in volume of white   –5%
                            mucus                                                                    Lowest           Highest
                                                           matter in key portions of the brain as
                                 0   25   50   75  100     revealed by the MRIs.                          Concentration of
                                   Percentage of children     Pollution even damages the sense            particulate matter
                                    showing symptoms                                          (a) Death rates increase with
                                                           of smell. In 2006–2008 Robyn Hudson   pollution intensity
                        Figure 1 Most Mexico City children   and colleagues ran lab experiments
                        show respiratory symptoms from air pol-  comparing Mexico City residents with   10
                        lution. Similar children from less-polluted   residents of a geographically similar
                        areas outside Mexico City show none   rural region with clean air. Hudson’s   8
                        of these conditions. Data from Calderón-  team presented the subjects with   6
                        Garcidueñas, L., et al., 2003. Respiratory damage   various smells at different intensities.
                        in children exposed to urban pollution. Pediatric   Compared with the rural residents,   4
                        Pulmonology 36: 148–161.           Mexico City residents had trouble     Percent change in likelihood of death  2
                                                           smelling distinct and familiar scents   0
                                                           such as orange juice and coffee. They   –2
                        Mexico City who had died at an early   also struggled to distinguish between
                        age. They found that pollution exacts   the common Mexican beverages      –4
                        a toll before the age of 18 and that   horchata and atole. The city-dwellers   –6
                        tiny bits of dead bacteria that cling   even had trouble noticing the stench   0  1   2   3   4   5
                        to pollutant particles are part of the   of rotting food! The researchers         Days after severe
                        problem. The heart mounts an inflam-  attributed this to tissue damage in the     pollution episode
                        matory response to try to repel the   noses of city-dwellers from a lifetime   (b) Infant mortality rates are higher
                        bacteria-laden particles, but because   of exposure to pollutants. Indeed,   after a pollution episode
                        the pollution is persistent, the inflam-  other scientists were documenting   Figure 2 rates of (a) death and
                        mation becomes chronic and stresses   such tissue damage with electron   (b) infant mortality each increase in
                        the heart.                         microscopy.                        Mexico City with the intensity of air   CHAPTER 17 • AT m os PHER i C   sC i E n CE , Ai R  Qu A li T y,  A nd Poll u T i on Con TR ol
                            Recent research also shows that   All these impacts can lead to   pollution. Data from (a) Borja-Aburto, V., et al.,
                        air pollution affects children’s brains,   higher rates of death. Studies by a   1997. Ozone, suspended particulates, and daily
                        sometimes leaving damage in brain   U.S. and Mexican research team    mortality in Mexico City. Am. J. Epidemiology
                        tissue that is similar to that seen in   in Mexico City in the late 1990s   145: 258–268; and (b) Loomis, D., et al., 1999.
                        Alzheimer’s disease. In one study using   confirmed this by comparing death   Air pollution and infant mortality in Mexico City.
                        brain scans, Calderón-Garcidueñas   certificate records against air pollution   Epidemiology 10: 118–123.
                        and her colleagues found that 56% of   measurements. The team found that
                        Mexico City youth had lesions on the   death rates rose on the day of and the   The extensive research showing
                        brain’s prefrontal cortex, whereas fewer   day after severe pollution episodes,   a diversity of health impacts from air
                        than 8% did in a region with clean air.   especially in response to particulate   pollution in Mexico City has caught the
                        Studies elsewhere, from Italy to Boston,   matter (Figure 2a). They also found that   attention of city leaders. These scientific
                        are finding similar results.       infant mortality was significantly higher   findings have helped push them to
                            In 2011, Calderón-Garcidueñas’s   in the days following strong pollution   work hard toward cleaning up their
                        team compared 20 children aged     episodes (Figure 2b).             city’s air.




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