Page 16 - Labatt Brain Tumour Research Centre Annual Report 2022 to 2023

YEAR IN REVIEW
Year in Review – Currently Held Grants
Dr. Sunit Das
Next generation precision oncology for pediatric- type AYA gliomas. Canadian Institutes of Health Research
Redefining the paradigm for surveillance in patients with low-grade glioma using saturation transfer magnetic resonance imaging. Canadian Institutes of Health Research
Optimizing brain tumour surveillance in Canada.
Canadian Cancer Society
Assessing molecular, clinical and imaging predictors of response, quality of life measures and neurocognitive outcomes in young adult patients with low grade glioma undergoing multimodality therapy. Brain Tumour Foundation of Canada
Improving outcomes across the cancer journey for adolescents and young adults with central nervous systems tumours: The IMPACT-CNS Cohort. Canadian Institutes of Health Research
Metabolic indicators of treatment response and survivorship in glioblastoma. Meagan’s HUG (Meagan Bebenek Foundation)
Dr. Peter Dirks
Determining the cellular mechanisms of initiation and evolution of hypermutant glioma. Canadian Institutes of Health Research
Targeting the transition between quiescent and activated stem cells in medulloblastoma. b.r.a.i.n.child
Tracing the cellular and molecular origins of mouse and human medulloblastoma. Canadian Institutes of Health Research
Terry Fox New Frontiers Program Project Grant in determinants of stemness that underlie high risk or relapse disease. Terry Fox Research Institute
A non-invasive approach to visualizing tumour growth in vivo through space and time. Canada Foundation for Innovation
Modeling brain cancer in regionally defined human neural stem cell system. Canadian Institutes of Health Research
Reimagining glioblastoma as a consequence of aberrant neural tissue repair. Canadian Cancer Society
The New Roads Team – Innovative approaches to curing brain tumours. Cancer Research UK
Targeting biological vulnerabilities of glioblastoma.
Cancer Research UK
Clinical translation of novel immune-based combination therapies for paediatric hypermutant cancers. Stand Up To Cancer
Targeting epigenetic dysregulation in pediatric cancers. Stand Up To Cancer
Epigenetic reorganization and differentiation of glioblastoma. Canadian Epigenetics, Environment and Health Research Consortium
Stem cell related genesis and maintenance of glioblastoma. Canadian Institutes of Health Research
Dr. Cynthia Hawkins
Next generation precision oncology for pediatric-type AYA gliomas. Canadian Cancer Society Research Institute
HSP90 inhibitor PU-HZ151 as a novel therapy for DIPG. Meagan’s HUG (Meagan Bebenek Foundation)
Integrated characterization of disseminated paediatric low-grade glioma. Rally Foundation
16 IMAGINE 2021-22