Page 7 - Information about Aloe Vera
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Aloe Vera 8.5 12pp final.qxd  1/15/06  2:22 PM  Page 7



                                                                                                      ALOE VERA
                                                                                                           the health benefits








                                       There has also been extensive and successful  measuring (assaying) it or upon investigating the
                                       work on use of Acemannan in cancer in living  mechanism by which it works. Payne (1970)
                                       animals in the 1990’s (Kent 1993), King et al  worked using Aloe in periodontal surgery. The
                                       (1991a), King et al (1991b), King et al (1995).  more rigorous scientific studies have been done in
                                                                                controlled experiments in which inflammation is
                                       No one should simply drink Aloe Gel or Extract  first created in a biological system using an irritant
                                       and expect to recover from cancer as a result.  and then noting the effects of Aloe treatment.
                                       That would be simplistic and almost certain to
                                       result in disappointment. There is insufficient  Davis et al (1984) and Davis et al (1987) measured
                                       evidence to justify this level of confidence. All one  the topical anti-inflammatory activity of Aloe vera by
                                       can say consuming high-specification Aloe  the relief of ear swelling caused by an irritant. Davis
                                       products may synergize with the effects from a  et al (1989a) administered processed Aloe vera
                                       very thorough-going nutritional programme.   topically, showing that it inhibits inflammation. Davis
                                                                                et al (1989b) and Davis et al (1992) used artificially
                                       6  Anti-Inflammatory Effect              created pouches of skin containing a specific irritant
                                       The anti-inflammatory action of Aloe in acute  such as croton oil or carrageenan (inflamed synovial
                                       inflammation is one of the best-known actions.  pouch method). Others have treated mouse skin to
                                       Aloe inhibits the complex tissue events that  produce minor trauma and then treated the skin, or
                                       accompany inflammation. The result is that the  the animal, with Aloe. There are numerous reports
                                       pain, soreness, redness and swelling associated  in this literature of various degrees of relief of
                                       with tissue damage diminish and pass off much  inflammation by Aloe, which is usually substantial


                                                                     Aloe, together with the nutrients                      Aloe reacts with or inhibits
                                                                     cited in the study, can be effective                   or destroys viruses or
                                                                     in improving the general health and                    cancer cells outside
                                                                     immune status of AIDS patients.                        the body.





                                       more rapidly than would otherwise be the case.  and mainly without any negative effects. This work
                                       This effect is clearly responsible for all the early  is well set out by Davis (1997).
                                       benefits from applying Aloe Gel or Whole Leaf
                                       Extract, or various preparations and ointments  There have by now been so many publications
                                       and creams of Aloe, to wounds, including  confirming anti-inflammatory activity that the
                                       operation wounds, cuts and abrasions of all kinds.  existence of the effect is in no doubt. We also
                                       This effect must also be responsible too for the  know of a range of different anti-inflammatory
                                       early benefits in sports injuries, such as sprains  substances in Aloe. The extent to which each
                                       and muscular injuries, frostbite, burns and  contributes to the overall anti-inflammatory effect
                                       radiation burns, in the tissue-damage applications  of Aloe gel or juice is not clear, however. It seems
                                       associated with dentistry and ear, nose and throat  that the compounds responsible for this effect are
                                       surgery, as well as its earliest effects upon  mostly small molecules because, when the higher
                                       arthritis and some infections. Many of the actions  molecular weight components of Aloe are
                                       of Aloe on other conditions that embody  precipitated out with alcohol (ethanol) some 78%
                                       inflammation must also be due at least in part to  of the anti-inflammatory activity remains in the
                                       the anti-inflammatory effect. This would include  supernatant liquid. The polysaccharide fractions of
                                       insect bites or stings and jellyfish stings. Much  Aloe are found mainly in the precipitate. Hence this
                                       skin disease is associated with inflammation as a  simple chemical process achieves a high degree of
                                       symptom. Clearly, Aloe often brings benefits from  separation of the immunostimulant from the anti-
                                       anti-inflammatory action, even though the skin  inflammatory components.
                                       trouble itself probably has a different primary
                                       cause. Hence the anti-inflammatory action is one  The substances in Aloe with anti-inflammatory
                                       of the main benefits of Aloe. It is one of those  properties include the natural steroids lupeol,
                                       actions that have favourable knock-on    beta-sitosterol and campesterol (Davis et al,
                                       consequences. The most dramatic benefits of  1994b, Davis et al, 1997), the enzyme,
                                       anti-inflammation are seen in acute conditions.  bradykininase, which is an enzyme breaking down
                                                                                the stimulatory peptide, bradykinin (Fujita et al
                                       Since the anti-inflammatory action is plain for all  1976, Yagi et al 1982, Yagi et al 1986), natural  page 5
                                       to see, most studies have focussed either upon  salicylates that bear a relationship to aspirin and
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