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106 CHAPTER 6: Neuropsy chiatric Genomics in Latin Americ a

Table 6.2 An Overview of Published Association Studies for Candidate
Genes and Neurological Diseases in Latin American Countries
Disease Country Genes Reference
Alzheimer’s disease Colombia APOE Arboleda et al. (2001)
Alzheimer’s disease Colombia A2M, ACE Camelo et al. (2004)
Alzheimer’s disease Colombia BDNF, COMT, Forero et al. (2006b)
UCHL1
Alzheimer’s disease Colombia LRP1, MAPT, Forero et al. (2006a)
SLC6A4
Alzheimer’s disease Brazil COMT Pereira et al. (2012)
Alzheimer’s disease Colombia PSEN1 (Mutations) Lalli et al. (2014)
Alzheimer’s disease Argentina PSEN2 (Mutations) Muchnik et al. (2015)
Alzheimer’s disease Brazil GAB2, BDNF Vieira et al. (2015)
Alzheimer’s disease Colombia TOMM40, CR1, Ortega-Rojas et al. (2016)
PVRL2, SORL1,
PICALM
Alzheimer’s disease Brazil DCHS2 Vieira et al. (2016)
Attention deficit and Brazil ADRA2A Roman et al. (2003)
hyperactivity disorder
Attention deficit and Brazil SLC6A3 Genro et al. (2007)
hyperactivity disorder
Attention deficit and Brazil SLC6A4, HTR2A Guimaraes et al. (2007)
hyperactivity disorder
Attention deficit and Brazil HRT1B Guimaraes et al. (2009a)
hyperactivity disorder
Attention deficit and Brazil DRD4 Tovo-Rodrigues et al.
hyperactivity disorder (2012)
Attention deficit and Brazil GIT1 Salatino-Oliveira et al.
hyperactivity disorder (2012a)
Attention deficit and Colombia ADRA2A Castro et al. (2013)
hyperactivity disorder
Attention deficit and Mexico COMT Martínez-Levy et al. (2013)
hyperactivity disorder
Attention deficit and Brazil NR3C2 Kortmann et al. (2013)
hyperactivity disorder
Attention deficit and Brazil SLC6A3 de Azeredo et al. (2014)
hyperactivity disorder
Attention deficit and Brazil GRM1, GRM5, Akutagava-Martins et al.
hyperactivity disorder GRM8 (CNVs) (2014b)
Attention deficit and Brazil GRM7 Akutagava-Martins (2014a)
hyperactivity disorder
Attention deficit and Colombia SNAP25 Gálvez et al. (2014)
hyperactivity disorder
Attention deficit and Brazil CDH13, CTNNA2 Salatino-Oliveira et al.
hyperactivity disorder (2015)
Attention deficit and Colombia DRD4, DRD5, Fonseca et al. (2015)
hyperactivity disorder SLC6A3, DBH,
HTR1B, SLC6A4
Attention deficit and Brazil NCAM1, TTC1, Mota et al. (2015)
hyperactivity disorder ANKK1, DRD2