Page 184 - Genomic Medicine in Emerging Economies

CHAPTER 10

The Genomic Medicine Alliance:

A Global Effort to Facilitate the

Introduction of Genomics into

Healthcare in Developing Nations

David N. Cooper*, Christina Mitropoulou**, Angela Brand ,
†
‡
Vita Dolzan , Paolo Fortina , Federico Innocenti , Ming T.M. Lee ††,‡‡ ,
¶
§
§§
Milan Macek Jr. , Konstantinos Mitropoulos**, Fahd Al-Mulla ,
¶¶
Barbara Prainsack***, Ron H. van Schaik ††† , Alessio Squassina ‡‡‡ ,
Domenica Taruscio ¶¶¶ , Effy Vayena §§§ , Athanassios Vozikis****,
Marc S. Williams , Bauke Ylstra †††† , George P. Patrinos ‡‡‡‡,§§§§§
††
*Institute of Medical Genetics, Cardiff University, Cardiff, United Kingdom;
†
**The Golden Helix Foundation, London, United Kingdom; University of Maastricht,
‡
Institute of Public Health Genomics, Maastricht, The Netherlands; University of
§
Ljubljana, Ljubljana, Slovenia; Thomas Jefferson University, Kimmel Cancer Center,
Philadelphia, PA, United States; Institute of Pharmacogenomics and Individualized
¶
††
Therapy, University of North Carolina, Chapel Hill, NC, United States; Genomic Medicine
Institute, Danville, PA, United States; RIKEN Center for Integrative Medical Sciences,
‡‡
¶¶
Yokohama, Japan; Charles University Prague, Institute of Biology and Medical Genetics,
Prague, Czech Republic; Kuwait University, Health Sciences Center, Kuwait City,
§§
***
Kuwait; King’s College London, London, United Kingdom; ††† Erasmus University
Medical Center, Rotterdam, The Netherlands; ‡‡‡ University of Cagliari, Cagliari,
Italy; ¶¶¶ National Centre for Rare Diseases, Istituto Superiore di Sanità, Rome, Italy;
§§§ University of Zurich, Epidemiology Biostatistics and Prevention Institute, Zurich,
Switzerland; **** University of Piraeus, Piraeus, Greece; †††† VU University Medical Center,
Amsterdam, The Netherlands; ‡‡‡‡ University of Patras School of Health Sciences, Patras,
Greece; §§§§§ United Arab Emirates University, Al-Ain, United Arab Emirates
INTRODUCTION
Genomic medicine aims to utilize the individual’s genomic information to
support the clinical decision-making process (Manolio et al., 2015). In recent
years, significant advances have been made in understanding the molecular
basis of a wide range of human inherited diseases and cancers with the poten-
tial to improve disease prognosis and treatment (Kilpinen and Barrett, 2013).

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Genomic Medicine in Emerging Economies. http://dx.doi.org/10.1016/B978-0-12-811531-2.00010-2
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