Page 18 - Parkview Antimicrobial Stewardship Guidebook_Neat

Antimicrobials in pregnancy

Antimicrobial Category Lactation
Amoxicillin B Enters milk-caution
Liposomal Amphotericin B B Unknown
Ampicillin/sulbactam B Enters milk-caution
Anidulafungin B Enters milk-caution
Azithromycin B Enters milk-caution
Aztreonam B Not recommended
Cefditoren B Unknown
Cefazolin B Enters milk-caution
Cefoxitin B Enters milk-caution
Ceftazidime +/- avibactam B Enters milk-caution
Ceftriaxone B Enters milk-caution
Cefepime B Enters milk-caution
Ceftaroline/ceftolozane-taz B Enters milk-caution
Ciprofloxacin C Not recommended
Clindamycin B Not recommended
Daptomycin B Enters milk-caution
Doxycycline/Minocycline D Not recommended
Ertapenem B Enters milk-caution
Fluconazole C/D^ Enters milk-caution
Fosfomycin B Enters milk-caution
Gentamicin C Enters milk-caution
Isavuconazole C Not recommended
Ketoconazole/posaconazole C Not recommended
Levofloxacin C Not recommended
Linezolid C Enters milk-caution
Meropenem B Enters milk-caution
Metronidazole B* Not recommended
Moxifloxacin C Not recommended
Nafcillin B Enters milk-caution
Nitrofurantoin B Not recommended
Penicillin B Enters milk-caution
TMP/sulfa C Enters milk-caution
Vancomycin IV C Not recommended
Vancomycin Oral B Preferred CDI treat
Voriconazole D Not recommended
^Category C for vulvovaginal candidasis 150mg x1; Category D for all other indications/doses

Pregnancy Category
A – Controlled studies show no risk
B – No evidence of risk in humans
C – Risk cannot be ruled out
D – Positive evidence of risk
X – Contraindicated in pregnancy