Page 6 - Parkview Antimicrobial Stewardship Guidebook_Neat

MICROBIOLOGY ANTIBIOGRAM DATA Jan-Dec 2015 (For Use through 2016)

PENICILLIN CEPHALO AG MAC- QUINO OTHER ANTIBIOTICS UTI
GRAM AND RELATED SPORINS LIDE LONES
POSITIVE
ORGANISMS Number of Isolates
Ampicillin Penicillin Cefazolin Ceftriaxone Gentamicin Azithromycin Levofloxacin Moxifloxacin Clindamycin Doxycycline Linezolid Daptomycin Vancomycin Nitrofurantoin
[PERCENT SUSCEPTIBLE] Oxacillin Septra

Staph aureus All Isolates 600 60 60 99 80 99 96 100 100 100 100
MRSA (Staph aureus) 240 70 99 95 100 100 100 100
Staph epidermidis 45 40 91 60 84 100 100 100 100
Enterococcus faecalis 166 100 100 100 100 98 100
Enterococcus faecium 19 16 16 100 90 21 80
Strep pneumoniae 40 50 97 98 95 76 74 100
^
Non-meningitis (IV dosing) 98 100
Meningitis (IV dosing) 63 100
COST (See Key) $$ $$$ $$$ $ $$ $ $ $ $ $$ $ $$ $$$$ $$$$ $$ $
^
MSSA : Methicillin Susceptible Staph aureus Note: Strep pneumoniae - If patient does not have meningitis and MIC < 2 then can often treat with IV Penicillin
~
MRSA: Methicillin Resistant Staph aureus (Isolates with Vancomycin MIC > 2 have high risk of clinical failure with vancomycin therapy) VRE: (Vancomycin Resistant Enterococcus)

PENICILLIN AND AMINO- QUINO- UTI
GRAM RELATED CEPHALOSPORINS GLYCIDES LONES OTHER ANTIBIOTICS

NEGATIVE (AG)
ORGANISMS
Number of Isolates
[PERCENT SUSCEPTIBLE] Cefazolin ^^ Ceftriaxone Ceftazidime Gentamicin Tobramycin Ciprofloxacin Levofloxacin Meropenem 2 Doxycycline Nitrofurantoin
Ampicillin Unasyn Zosyn Cefepime Aztreonam Septra

E coli ^ 1193 54 60 99 94 95 93 79 79 95 99 76 80 97
^
Kleb pneumoniae 257 90 99 99 99 99 98 98 99 100 96 91 67
Kleb oxytoca 46 74 100 100 100 98 100 100 100 100 98 94
Proteus mirabilis 72 71 77 100 90 97 82 56 66 97 100 60
Enterobacter cloacae* 56 93 86 100 98 98 86 99 89 86
Enterbcter aerogenes* 24 96 92 100 100 100 96 100 96 92
Serratia marcescens* 11 100 73 91 82 100 100 100 91
Citrobacter freundii* 24 96 92 83 92 96 92 100 83 83 100
Pseudo aeruginosa* 183 99 96 93 87 98 81 82 91 90
COST (See Key) $$ $ $$$ $ $ $$ $$ $$ $$ $ $ $$$ $$$$ $$$$ $$ $
^
*IB - possess Inducible Beta Lactamase (may become resistant to all Beta Lactam drugs) ESBL Extended Spectrum Beta Lactamases = 2.7% (41 E coli / 1 Kleb / 1 Proteus 2015)

Steno maltophilia: drug of choice Septra (100% Susceptible in 2015) CRE Carbapenem Resistant – 2 E cloacae CRAB Carbapenem Resistant Acineto = 4 A baumannii
2 ^^
Meropenem on PMC formulary will be substituted for Imipenem by Pharmacy Revised Breakpoints for Cefazolin Ecoli, Kleb & Proteus in Urinary Tract
4

CEPHALO- MACROLIDES QUINO- OTHER ANTIBIOTICS

PENICILLIN
OTHER AND RELATED* SPORINS* LONE
ORGANISMS
Number of Isolates
[PERCENT SUSCEPTIBLE]
Ampicillin Penicillin Cefazolin Cefotaxime Ceftriaxone Azithromycin Erythromycin Levofloxacin Clindamycin Septra Doxycycline

Haemophilus influenza 69 70 100 100 96 100 64 54
Group A Beta Strep* 43 100 100 100 100 93 74 100 77 86
Group B Beta Strep* 40 * * * 62 73
COST (See Key) $$ $$$ $ $ $ $ $$ $ $$ $ $$

* Beta-Strep: predictably sensitive to Penicillins and Beta lactams Group A Beta Strep - Sterile Body Fluid Isolates/Upper Respiratory Isolate