Page 7 - Parkview Antimicrobial Stewardship Guidebook_Neat

PARKVIEW MEDICAL CENTER MICROBIOLOGY

ANAEROBIC ANTIBIOGRAM (DATA 2014-2015)**

PENICILLIN AND RELATED CEPHALO OTHER ANTIBIOTICS
SPORIN
ANAEROBIC
ORGANISMS

[PERCENT SUSCEPTIBLE] No. Isolates Augmentin Meropenem 2 Clindamycin Metronidazole
Penicillin Unasyn Zosyn Cefoxitin

Bacteroides fragilis 1* 16 100 100 100 100 63 81 100
81
100
91
97
100

72
93
44
58
Bacteroides fragilis group
100
100
100
100
10
30
Bact. thetaiotaomicron
50
36
86
100
100
100
100
Prevotella melaninogenica
13
69
100
100
100
100
100
GRAM NEGATIVE ANAEROBES Bacteroides ovatus 14 100 100 100 100 100 57 100
50
6
100
Prevotella bivia
100
100
100
100
100
Prevotella buccae / disiens
16
63
94
100
100
100
100
100
Prevotella species *
18
94
39
88
Fusobacterium nucleatum
100
100
100
100
100
100
100
Fusobacterium necrophorum
9
100
100
100
100
100
15
92
100
100
Clostridium perfringens 17 100 100 100 100 100 100 100 100
100
100
100
100
100
83
100
12
100
Peptostrep asaccharolyticus
82
GRAM POSITIVE ANAEROBES Finegoldia magna 11 100 100 100 100 100 100 100 100
96
100
0
100
100
100
100
26
Proprionobacterium acnes
Eggerthella lenta 12 25 100 100 92 100 83 100 100
COST $$$ $$$ $ $$$ $$$$ $$ $$ $

1
B fragilis group includes B. fragilis, thetaiotaomicron, distasonis, ovatus, vulgaris * (Group ID unable to speciate with biochemical testing)

2 Meropenem on PMC formulary will be substituted for Imipenem by Pharmacy
Anaerobes are tested using E test gradient method. Isolates are from sterile body sites, abscesses, pure culture, etc.

**Two year data for Anaerobic Susceptibility Testing - Periodic monitor of PMC susceptibility data.

Note – concerning Antibiogram data provided for all charts:

a
Percent susceptible for each organism/antibiotic combination was generated by including the first isolate encountered on patient/source
Isolates with <30 total have less statistical validity of the estimate of %Susceptible. Cost Key – IV Route
Primary susceptibility method - Broth Microdilution Additional methods - Kirby Bauer Disk Diffusion and E Test gradient MIC $ = $0-$10 $$$ = $55-$120

[ ] Antibiotic information/data may be available. Data interpreted/compiled according to CLSI documents M100 S25 2015 $$ = $11-$54 $$$$ = $121-$250
and M11 A7 Vol 27 No 2 2007 and M39-A3 2009. Revised Breakpoints for Cephalosporins & Carbapenems began August 2012

ANTIBIOGRAM

MICROBIOLOGY LABORATORY
Ex 4438
Paul McCarthy MD Medical Director Lab-Pathology
Melinda Lanning MT(ASCP) Microbiology Supervisor Ex 4799
Phil Helfter RPh Pharmacy Ex 4751 Jatin Patel MD (Infectious Diseases)
Available at www.parkviewmc.com or PMC intranet – Clinical Resources or Physician tabs