Page 48 - Pharmacology Mnemonics and Short Notes

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One drug bind to receptor without activating it and prevents the
binding of agonist (thus prevent activation by agonist)

Types

 Competitive

 Non competitive

Competitive

A pharmacological antagonism in which effect of antagonist can be
overcome by increase in concentration of agonist

 There is competition between antagonist and

agonist  whose concentration is more will

dominate
 Drug will closely resemble the agonist and will bind reversibly to the

receptor without activating the receptor

Non-competitive

A pharmacological antagonism in which the effect of antagonist cannot

be overcome by increase in concentration of agonist

 There is no competition But antagonist bind
irreversibly and do not allow the agonist to bind

 Drug will bind to receptor irreversibly

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Pharmacology Mnemonics and Short Notes By Muhammad Ramzan Ul Rehman