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Klingeborn et al.                                                                  Page 41















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                               Figure 2. Extensive subfractionation of EV preparations identified highly enriched and/or
                               specific markers for different subsets of EVs
                               Exosomes make up a subset of tetraspanin positive small EVs (sEVs), here identified by
                               Syntenin-1, TSG101 and CD81. Figure from (Kowal et al., 2016); with permission and
                               copyright PNAS. Permission Pending.

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                                  Prog Retin Eye Res. Author manuscript; available in PMC 2018 July 01.
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