Page 22 - BB Neuromedicine Highlights 2019
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While this does not offer any di-
                                                                                           rect treatment options, it does en-
                                                                                           able researchers to have access to
                                                                                           brain tissue for study. This means
                                                                                           that there is an acceleration in the
                                                                                           capacity to understand neuro-
                                                                                           logical diseases and research the
                                                                                           effects of new drugs. For example,
                                                                                           stem cells from a Parkinson’s
                                                                                           disease patient could recreate
                                                                                           a “Parkinson’s brain” for active
                                                                                           research. Not only does this avoid
                                                                                           animal research, it speeds up the
                                                                                           investigative process as well.

                                                                                           challeNges aheaD FOr
                                                                                           NeurOlOgIcal sTem cell
                                                                                           TechNOlOgy
                                                                                             Several obstacles exist for 3D
        neurological disorders in the very   of Minnesota, researchers have   aDvaNcINg care ThrOugh   printing for medical use. For one,
        near future. Specifically, neurolog-  successfully used 3D printing   research     all tissues need blood circulation.
        ical stem cell technology could be   for medical use to help these   Indeed, 3D printing for medical   Matching up a person’s existing
        a key to treatments in Parkinson’s   individuals.      use and neurological stem cell   blood vessels with that of 3D-print-
        disease, epilepsy, brain trauma,   Funded by Conquer Paralysis   technology is exciting in terms   ed tissues poses a challenge. Like-
        and even schizophrenia. In es-  Now, specialized stem cells are   of new disease treatments. But   wise, some stem cell types have
        sence, 3D printing for medical use   printed onto a silicone structure.   other companies are advancing   the potential for developing into
        could allow neurological stem cell   this structure is then inserted as   discoveries by facilitating neuro-  tumors called teratomas. However,
        technology to replace dysfunction   a “bridge” between healthy spinal   logical research. Celprogen, Inc.,   ongoing research is actively looking
        or degenerative neurons.    cord areas. Researchers are find-  is recognized as a bold business   to solve these problems. And thus
          At the University of Wollongong   ing that roughly three-quarters of   leader in stem cell research and   far, there clearly spells progress.
        in Australia, researchers have   the stem cells are surviving, which   therapeutics. Recently, the com-  Given the speed at which these
        been pursuing this approach   is a marked improvement. Thus,   pany successfully used 3D printing   developments are proceeding, 3D
        for over a year. They printed   this form of neuromedicine could   for medical use to recreate an   printing for medical use is likely
        pluripotent stem cells onto a 3D   offer a radical new option of care.  entire brain from stem cells.  right around the corner.
        scaffold to create neurons that
        made specific brain chemicals.
        The goal is to then place these
        cells in the brains of patients with
        specific conditions lacking these
        neurotransmitters. This is how
        neurological stem cell technology
        could restore function to a variety
        of neurological illnesses.

        majOr heaDWay FOr sPINal
        cOrD INjury TreaTmeNT
          In addition to treating neu-
        rological diseases of the brain,
        neurological stem cell technology
        also offers promise for spinal cord
        injuries. In the U.S., over 17,000
        new spinal cord injuries occur
        each year with notable disabili-
        ties. However, at the University
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