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PF-07302048 (BNT162 RNA-Based COVID-19 Vaccines)
Protocol C4591001

Abbreviation Term
MCHC mean corpuscular hemoglobin concentration
MCV mean corpuscular volume
MedDRA Medical Dictionary for Regulatory Activities
MERS Middle East respiratory syndrome
MIS-C multisystem inflammatory syndrome in children
modRNA nucleoside-modified messenger ribonucleic acid
MRI magnetic resonance imaging
N SARS-CoV-2 nucleoprotein
N/A not applicable
NAAT nucleic acid amplification test
non-S nonspike protein
P2 S SARS-CoV-2 full-length, P2 mutant, prefusion spike glycoprotein
PaO2 partial pressure of oxygen, arterial
PCR polymerase chain reaction
PI principal investigator
POS probability of success
PPE personal protective equipment
PT prothrombin time
RBC red blood cell
RBD receptor-binding domain
RCDC reverse cumulative distribution curve
RNA ribonucleic acid
RR respiratory rate
RSV respiratory syncytial virus
RT-PCR reverse transcription–polymerase chain reaction
S1 spike protein S1 subunit
SAE serious adverse event
SAP statistical analysis plan
saRNA self-amplifying messenger ribonucleic acid
SARS severe acute respiratory syndrome
SARS-CoV-2 severe acute respiratory syndrome coronavirus 2
SBP systolic blood pressure
SoA schedule of activities
SOP standard operating procedure
SpO2 oxygen saturation as measured by pulse oximetry
SRSD single reference safety document
SUSAR suspected unexpected serious adverse reaction
TBD to be determined
TBili total bilirubin
ULN upper limit of normal
uRNA unmodified messenger ribonucleic acid
US United States
vax vaccination

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