Page 8 - Equine influenza e-Book
P. 8

Subsequent management


        Treatment


       •  Rest: 1 week for every day of fever.
       •  Monitor for secondary bacterial infection and provide antibiotic cover Therapeutics: antimicrobials if
           appropriate.


        Monitoring

       •  Clinical signs.


        Prevention



        Control


       •  Vaccination Equine influenza vaccine.


          Vaccination in the presence of maternal antibodies is not recommended as it may → the
          induction of tolerance, therefore start vaccination of foals at 6-9 months when maternal
          antibodies have declined. Foals from non-vaccinated mares can be vaccinated at 3 months.


       •  Primary vaccine course: 2 doses 21-90 days apart.
       •  Booster vaccination 150-215 days after second injection of primary course.
       •  Subsequent boosters at least every 12 months (younger animals may require boosters every 4-6
           months).
       •  Boosters to be given more often if at risk, eg transported to race tracks.
       •  The efficacy of a vaccination is determined by its hemagglutinin content (measured by single radial
           immunodiffusion).
       •  Live inactivate vaccines are effective; killed vaccines are not effective.
       •  Vectored vaccines are available, eg Proteq Flu uses canarypox vector have shown to induce a wider
           range of immunity.
       •  Formal surveillance by OIE and WHO is carried out and then they advise on the best strain to include in
           the vaccines.
       •  The majority of epidemics occur when horses are vaccinated with out of date vaccines which only induce
           partial immunity.


        Prophylaxis


       •  Equine influenza vaccines Equine influenza vaccine.
       •  Some are combined with tetanus toxoid.
       •  Protective efficacy of vaccines may decrease due to antigenic drift of virus strains.


        Group eradication


       •  Vaccination.
       •  Isolate young animals.
       •  Vaccinate mares 1 month prior to parturition Reproduction: management - female.


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