Page 17 - Medicine and Surgery
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P1: JYS
         BLUK007-01  BLUK007-Kendall  May 12, 2005  17:17  Char Count= 0







                                                                              Chapter 1: Perioperative care 13


                  Clinical features
                                                                 Perioperative care
                  The condition may be asymptomatic and diagnosed in-
                  cidentally on calcium measurement.
                                                                The preoperative assessment
                  Neuromuscular manifestations                  Underlying any decision to perform surgery is a recog-
                  Early symptoms include circumoral numbness, paraes-  nition of the balance between the risk of the procedure
                  thesiae of the extremities and muscle cramps. Common  and the potential benefits to the patient. All patients un-
                  but less specific symptoms include fatigue, irritability,  dergo a preoperative assessment (history, examination
                  confusion and depression. Myopathy with muscle weak-  and appropriate investigations) both to review the diag-
                  ness and wasting may be present. Carpopedal spasm  nosis and need for surgery, and to identify any coexisting
                  and seizures are signs of severe hypocalcaemia. Elici-  disease that may increase the likelihood of perioperative
                  tation of Trousseau’s sign and Chvostek’s signs should  complications. In general any concerns regarding coex-
                  be attempted, although it can be negative even in severe  isting disease or fitness for surgery should be discussed
                  hypocalcaemia:                                with the anaesthetist who makes the final decision re-
                    Trousseau’s sign: Carpal spasm induced by inflation of  garding fitness for anaesthesia.

                    asphygmomanometerabovesystolicBPfor3minutes.
                    Chvostek’s sign: Contraction of the ipsilateral facial  Cardiac disease

                    muscles (including the eye, nose and corner of the  Ischaemic heart disease remains the most important risk
                    mouth) after tapping the facial nerve anterior to the  factorforpatientsundergoingsurgery.Itisvitalaspartof
                    ear.                                        apreoperative assessment to identify underlying cardiac
                  The BP may be low despite fluids or inotropes. Cardiac  disease by history, examination and, where appropriate,
                  failure may occur.                            investigations. An ECG should be performed in any pa-
                    Other findings may include papilloedema and in  tient with a history suggestive of cardiac disease and in
                  chronic cases cataracts, dry puffy coarse skin with brittle  all patients over 50 years of age.
                  and thinned hair and nails.                      Following a myocardial infarction the risk of re-
                                                                 infarction is maximal over subsequent 6 weeks, if
                  Investigations                                 surgery is performed the re-infarction rate increases
                  These are aimed at assessing the severity of hypocal-  dramatically. Elective surgery should be deferred by at
                  caemia to guide management and to look for the under-  least 6 months wherever possible.
                  lying cause. The serum calcium should be checked and     Hypertension should be controlled prior to any elec-
                  corrected for serum albumin (see above). Blood should  tive surgery to reduce the risk of myocardial infarction
                  also be sent for magnesium, phosphate, U&Es and for  or stroke. Specialist cardiac advice may be required
                  PTH level. An ECG should be done to look for ECG  prior to emergency surgery in severely hypertensive
                  changes (increased QT interval, cardiac arrhythmias).  patients.
                  Other investigations depend on the suspected cause.     Arrhythmias should ideally be corrected prior to
                                                                 surgery. Chronic or complex arrhythmias should be
                  Management                                     discussedwithacardiologistpriortosurgerywherever
                  This depends on the severity, whether acute or chronic  possible.
                  and the underlying cause. Mild hypocalcaemia is treated     Patients with signs and symptoms of cardiac failure
                  with oral supplements of calcium and magnesium  should have their therapy optimised prior to surgery
                  where appropriate. Severe hypocalcaemia may be life-  and require special attention to perioperative fluid
                  threatening and the first priority is resuscitation as  balance.
                  needed (e.g. management of seizures or cardiac arrhyth-     Patients with abnormal or prosthetic heart valves,
                  mias),followedbytheadministrationofintravenouscal-  patent ductus arteriosus or septal defects, and patients
                  cium. Calcium gluconate contains only a third of the  with a history of bacterial endocarditis should have
                  amount of calcium as calcium chloride but is less irritat-  prophylactic oral or intravenous antibiotic cover for
                  ing to the peripheral veins.                   any surgical procedures.
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