Page 68 - Medicine and Surgery
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                   64 Chapter 2: Cardiovascular system


                     pleural effusions and Kerley B lines. In acute pul-  can aggravate myocardial ischaemia and cause further
                     monary oedema there may be ‘bat wing’ or ground  reductionincardiac output.
                     glass pulmonary shadowing.
                     Blood gases: There is an initial fall in arterial pO 2 and  Clinical features

                     pCO 2 due to hyperventilation. As the patient tires or  The patient has cool peripheries with a rapid low vol-
                     in severe cases the pCO 2 rises.           ume pulse. There is tachypnoea, oligo/anuria and ex-
                     Other investigations include ECG and an echocardio-  treme distress. There may be associated symptoms of

                     gram to look for the underlying cause.     left ventricular failure, including pulmonary oedema.

                   Management                                   Investigations
                     The patient is placed in the sitting position and should     ECG to look for evidence of myocardial infarction or

                     be given high flow oxygen. Careful fluid balance is  any cardiac arrhythmias.
                     essential and may include urinary catheterisation.     Chest X-ray to look for evidence of cardiomegaly and
                     Additional ventilatory support may be required in-  cardiac failure (see page 62).

                     cluding continuous positive airway pressure.     Echocardiogramshouldideallybeperformedurgently
                     Intravenous diuretic gives immediate venodilatation  to identify any correctable valve lesions and assess car-

                     and later increased renal fluid excretion.    diac structure and function.
                     Intravenous diamorphine (with an antiemetic) re-

                     duces distress, venodilates and relieves dyspnoea.
                                                                Management
                     Intravenous glyceryl trinitrate is used to venodilate

                                                                    Patients require intensive care, high flow oxygen and
                     and thus reduce the cardiac preload.
                                                                  careful fluid management.
                     Aminophylline infusion can be considered if there is

                                                                    Cardiac inotropes are usually necessary to maintain
                     bronchoconstriction. It also increases vasodilatation
                                                                  systemic blood pressure. Increasing skin temperature
                     and increases cardiac contractility.
                                                                  and oxygen saturation are a guide to improvement.
                     If patient is hypertensive hydralazine or diazoxide (ar-

                                                                    Any cardiac arrhythmia should be corrected and
                     terial dilators) can be used to reduce cardiac afterload
                                                                  angioplasty considered in patients with cardiogenic
                     and hence increase stroke volume.
                                                                  shock in the setting of acute myocardial infarction.
                     Any underlying problem such as arrhythmia should

                                                                    Intra-aortic balloon pumping may be instituted but it
                     be corrected.
                                                                  does not improve mortality unless there is an under-
                                                                  lying correctable cause.
                   Cardiogenic shock                                Surgical intervention may be life saving in cases of
                                                                  mitralvalveincompetence,acquiredventricularseptal
                   Definition
                                                                  defect or critical coronary artery disease.
                   Severe circulatory failure resulting from a low cardiac
                   output usually characterised by severe hypotension.
                                                                Prognosis
                                                                Mortality of 80%.
                   Aetiology
                   This is an extreme type of acute cardiac failure the most
                   common cause of which is myocardial infarction. Other  Chronic cor pulmonale
                   causes include acute severe valve incompetence, or ven-
                                                                Definition
                   tricular septal defect post-MI.
                                                                Right-sidedheartfailureresultingfromchroniclungdis-
                                                                ease.
                   Pathophysiology
                   Cardiogenic shock is severe heart failure despite an ad-
                   equate or elevated central venous pressure, distinguish-  Incidence
                   ing it from hypovolaemic or septic shock. Hypotension  Commonest cause of pulmonary hypertensive heart dis-
                   may result in a reduction in coronary blood flow, which  ease.
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