Page 5 - eBook-CBD-englisch
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1.2 ENDOCANNABINOIDS
Cannabinoids that are naturally produced in the human body are called
endocannabinoids.
They are formed within body fatty acids such as omega-6.
The two major endocannabinoids that are well understood today are
Anandamide, the first endocannabinoid discovered by scientists. It is found in
higher concentrations outside the brain.
2-AG (2-eachidonoylglycerol): Highest concentration occurs in the brain.
These endocannabinoids are called "short-term" neurotransmitters because
they are only synthesized when the body signals that it needs them acutely.
Once released, they are quickly broken down by enzymes such as FAAH (fatty
acid a- midhydrolase) and MAGL (monoacylglycerol lipase). There are many
other endocannabinoids like Noladinether, Virodhamin and
N-arachidonoyldopamine (NADA).
However, its role in the body has not yet been fully decoded. The body
produces endocannabinoids to trigger essential bodily functions and patterns.
Ethan Russo believes that "deficient cannabinoid levels can be the underlying
cause of numerous diseases.
This deficiency could possibly cause serious diseases such as chronic pain or
fibromyalgia, which are related to the endocannabinoid system.
