Page 19 - E-bookANA
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Fine speckled pattern (AC-4)
Hep-2 cells, show a fine speckled fluorescence of the cell nuclei in
the interphase. the nucleoli are also reactive, but they are slightly
silhouetted against the nucleoplasm In some samples they do react
at all Mitotic cells show a speckled fluorescence, with
the chromosomes excluded.
Primate liver, there is no speckled reaction in the hepatocyte
nuclei but the nuclei show a smooth fluorescence in sample with
a high antibody titer
