Page 19 - E-bookANA
P. 19

16



                            Fine speckled pattern (AC-4)


































































             Hep-2 cells, show a fine speckled fluorescence of the cell nuclei in



             the interphase. the nucleoli are also reactive, but they are slightly



             silhouetted against the nucleoplasm In some samples they do react



             at all Mitotic cells show a speckled fluorescence, with



             the chromosomes excluded.







































































              Primate liver, there is no speckled reaction in the hepatocyte



              nuclei but the nuclei show a smooth fluorescence in sample with




              a high antibody titer
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