Page 7 - GDG676 Handbook
P. 7
The Reaction
Allergen exposure
Antigen
Plasma cells
produce igE Plasma cell
antibodies against
the allergen
IgE
IgE antibodies Mast cell with fixed
attach to mast igE antibodies
cells and baso-
phils
Granules containing
histamine
More of same
allergen enters Allergen
the body
Mast cell granules
release contents
after antigen binds
with igE antibodies
Histamines and other
mediators
3