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Chapter 7: Advanced Imaging: Spinal Surgery  77

                 The differential diagnosis for extradural lesions includes   primary lesion or from edema secondary to the primary lesion is
               intervertebral disc herniation, ligamentous hypertrophy, hemor­  often evident. Intravenous contrast enhancement may be present
               rhage, neoplasia (vertebral or soft tissue), abscess, and vertebral   with CT or MRI if there is breakdown of the blood–spinal cord bar­
               fracture or luxation.                              rier. The differential diagnosis for intramedullary lesion includes
                 Intramedullary lesions are characterized by enlargement of the   spinal cord edema, ischemic myelopathy, neoplasia, and inflamma­
               spinal cord and deviation of the subarachnoid space toward the ver­  tory disease. Neoplasia and ischemia tend to be focal lesions while
               tebral canal on all projections (outward deviation) (Figure 7.7C).   inflammatory disease is more commonly multifocal.
               With myelography and CT, enlargement may be the only finding   Intradural–extramedullary lesions (Figure  7.7D) are most
               unless there is a tear in the dura resulting in contrast diffusion into     evident  when  there  is  contrast  medium  in  the  subarachnoid
               the spinal cord. With MRI, a change in signal intensity due to the   space or on heavily T2‐weighted MRI (myelogram‐like images).


                                A















                                B














                                C














                                D














               Figure 7.7  Lateral (sagittal), ventrodorsal (dorsal), and transverse representations of the subarachnoid space in normal (A), extradural (B), intramedullary
               (C), and intradural–extramedullary (D) spinal cord lesions.
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